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Ligand and Target Discovery by Fragment-Based Screening in Human Cells.
Parker CG, Galmozzi A, Wang Y, Correia BE, Sasaki K, Joslyn CM, Kim AS, Cavallaro CL, Lawrence RM, Johnson SR, Narvaiza I, Saez E, Cravatt BF. Parker CG, et al. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19. Cell. 2017. PMID: 28111073 Free PMC article.
The Druggability of Solute Carriers.
Wang WW, Gallo L, Jadhav A, Hawkins R, Parker CG. Wang WW, et al. Among authors: parker cg. J Med Chem. 2020 Apr 23;63(8):3834-3867. doi: 10.1021/acs.jmedchem.9b01237. Epub 2019 Dec 19. J Med Chem. 2020. PMID: 31774679 Review.
Chemoproteomic-enabled phenotypic screening.
Conway LP, Li W, Parker CG. Conway LP, et al. Among authors: parker cg. Cell Chem Biol. 2021 Mar 18;28(3):371-393. doi: 10.1016/j.chembiol.2021.01.012. Epub 2021 Feb 11. Cell Chem Biol. 2021. PMID: 33577749 Free article. Review.
A Sos proteomimetic as a pan-Ras inhibitor.
Hong SH, Yoo DY, Conway L, Richards-Corke KC, Parker CG, Arora PS. Hong SH, et al. Among authors: parker cg. Proc Natl Acad Sci U S A. 2021 May 4;118(18):e2101027118. doi: 10.1073/pnas.2101027118. Proc Natl Acad Sci U S A. 2021. PMID: 33926964 Free PMC article.
Targeted Protein Acetylation in Cells Using Heterobifunctional Molecules.
Wang WW, Chen LY, Wozniak JM, Jadhav AM, Anderson H, Malone TE, Parker CG. Wang WW, et al. Among authors: parker cg. J Am Chem Soc. 2021 Oct 13;143(40):16700-16708. doi: 10.1021/jacs.1c07850. Epub 2021 Sep 30. J Am Chem Soc. 2021. PMID: 34592107 Free PMC article.
A Chemical Proteomic Map of Heme-Protein Interactions.
Homan RA, Jadhav AM, Conway LP, Parker CG. Homan RA, et al. Among authors: parker cg. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12. J Am Chem Soc. 2022. PMID: 35960875 Free PMC article.
77 results