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Page 1
Single cell derived mRNA signals across human kidney tumors.
Young MD, Mitchell TJ, Custers L, Margaritis T, Morales-Rodriguez F, Kwakwa K, Khabirova E, Kildisiute G, Oliver TRW, de Krijger RR, van den Heuvel-Eibrink MM, Comitani F, Piapi A, Bugallo-Blanco E, Thevanesan C, Burke C, Prigmore E, Ambridge K, Roberts K, Braga FAV, Coorens THH, Del Valle I, Wilbrey-Clark A, Mamanova L, Stewart GD, Gnanapragasam VJ, Rampling D, Sebire N, Coleman N, Hook L, Warren A, Haniffa M, Kool M, Pfister SM, Achermann JC, He X, Barker RA, Shlien A, Bayraktar OA, Teichmann SA, Holstege FC, Meyer KB, Drost J, Straathof K, Behjati S. Young MD, et al. Among authors: custers l. Nat Commun. 2021 Jun 23;12(1):3896. doi: 10.1038/s41467-021-23949-5. Nat Commun. 2021. PMID: 34162837 Free PMC article.
An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity.
Calandrini C, Schutgens F, Oka R, Margaritis T, Candelli T, Mathijsen L, Ammerlaan C, van Ineveld RL, Derakhshan S, de Haan S, Dolman E, Lijnzaad P, Custers L, Begthel H, Kerstens HHD, Visser LL, Rookmaaker M, Verhaar M, Tytgat GAM, Kemmeren P, de Krijger RR, Al-Saadi R, Pritchard-Jones K, Kool M, Rios AC, van den Heuvel-Eibrink MM, Molenaar JJ, van Boxtel R, Holstege FCP, Clevers H, Drost J. Calandrini C, et al. Among authors: custers l. Nat Commun. 2020 Mar 11;11(1):1310. doi: 10.1038/s41467-020-15155-6. Nat Commun. 2020. PMID: 32161258 Free PMC article.
Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours.
Custers L, Khabirova E, Coorens THH, Oliver TRW, Calandrini C, Young MD, Vieira Braga FA, Ellis P, Mamanova L, Segers H, Maat A, Kool M, Hoving EW, van den Heuvel-Eibrink MM, Nicholson J, Straathof K, Hook L, de Krijger RR, Trayers C, Allinson K, Behjati S, Drost J. Custers L, et al. Nat Commun. 2021 Mar 3;12(1):1407. doi: 10.1038/s41467-021-21675-6. Nat Commun. 2021. PMID: 33658498 Free PMC article.
In vitro Modeling of Embryonal Tumors.
Custers L, Paassen I, Drost J. Custers L, et al. Front Cell Dev Biol. 2021 Feb 26;9:640633. doi: 10.3389/fcell.2021.640633. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33718380 Free PMC article. Review.
Neuroblastoma and DIPG Organoid Coculture System for Personalized Assessment of Novel Anticancer Immunotherapies.
M Kholosy W, Derieppe M, van den Ham F, Ober K, Su Y, Custers L, Schild L, M J van Zogchel L, M Wellens L, R Ariese H, Szanto CL, Wienke J, Dierselhuis MP, van Vuurden D, Dolman EM, Molenaar JJ. M Kholosy W, et al. Among authors: custers l. J Pers Med. 2021 Aug 30;11(9):869. doi: 10.3390/jpm11090869. J Pers Med. 2021. PMID: 34575646 Free PMC article.
CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells.
Lopes R, Korkmaz G, Revilla SA, van Vliet R, Nagel R, Custers L, Kim Y, van Breugel PC, Zwart W, Moumbeini B, Manber Z, Elkon R, Agami R. Lopes R, et al. Among authors: custers l. Cancer Lett. 2018 Nov 1;436:87-95. doi: 10.1016/j.canlet.2018.08.018. Epub 2018 Aug 23. Cancer Lett. 2018. PMID: 30145202 Free article.