Zhang Q - Search Results

1

Strategies for Targeting Serine/Threonine Protein Phosphatases with Small Molecules in Cancer.

Zhang Q, Fan Z, Zhang L, You Q, Wang L. Zhang Q, et al. Among authors: zhang l. J Med Chem. 2021 Jul 8;64(13):8916-8938. doi: 10.1021/acs.jmedchem.1c00631. Epub 2021 Jun 22. J Med Chem. 2021. PMID: 34156850 Review.

2

Discovery and Optimization of Small Molecules Targeting the Protein-Protein Interaction of Heat Shock Protein 90 (Hsp90) and Cell Division Cycle 37 as Orally Active Inhibitors for the Treatment of Colorectal Cancer.

Wang L, Jiang J, Zhang L, Zhang Q, Zhou J, Li L, Xu X, You Q. Wang L, et al. Among authors: zhang l, zhang q. J Med Chem. 2020 Feb 13;63(3):1281-1297. doi: 10.1021/acs.jmedchem.9b01659. Epub 2020 Jan 24. J Med Chem. 2020. PMID: 31935086

3

Design, synthesis and bioevaluation of inhibitors targeting HSP90-CDC37 protein-protein interaction based on a hydrophobic core.

Zhang Q, Wu X, Zhou J, Zhang L, Xu X, Zhang L, You Q, Wang L. Zhang Q, et al. Among authors: zhang l. Eur J Med Chem. 2021 Jan 15;210:112959. doi: 10.1016/j.ejmech.2020.112959. Epub 2020 Oct 22. Eur J Med Chem. 2021. PMID: 33109397

4

Targeting the HSP90-CDC37-kinase chaperone cycle: A promising therapeutic strategy for cancer.

Wang L, Zhang Q, You Q. Wang L, et al. Among authors: zhang q. Med Res Rev. 2022 Jan;42(1):156-182. doi: 10.1002/med.21807. Epub 2021 Apr 12. Med Res Rev. 2022. PMID: 33846988 Review.

5

Plant accumulation and transformation of brominated and organophosphate flame retardants: A review.

Zhang Q, Yao Y, Wang Y, Zhang Q, Cheng Z, Li Y, Yang X, Wang L, Sun H. Zhang Q, et al. Environ Pollut. 2021 Nov 1;288:117742. doi: 10.1016/j.envpol.2021.117742. Epub 2021 Jul 7. Environ Pollut. 2021. PMID: 34329057 Review.

6

A review of organophosphate esters in soil: Implications for the potential source, transfer, and transformation mechanism.

Zhang Q, Wang Y, Zhang C, Yao Y, Wang L, Sun H. Zhang Q, et al. Among authors: zhang c. Environ Res. 2022 Mar;204(Pt B):112122. doi: 10.1016/j.envres.2021.112122. Epub 2021 Sep 24. Environ Res. 2022. PMID: 34563524 Review.

7

Methods for the Discovery and Identification of Small Molecules Targeting Oxidative Stress-Related Protein-Protein Interactions: An Update.

Wu X, Zhang Q, Guo Y, Zhang H, Guo X, You Q, Wang L. Wu X, et al. Among authors: zhang q, zhang h. Antioxidants (Basel). 2022 Mar 23;11(4):619. doi: 10.3390/antiox11040619. Antioxidants (Basel). 2022. PMID: 35453304 Free PMC article. Review.

8

Beyond Proteolysis-Targeting Chimeric Molecules: Designing Heterobifunctional Molecules Based on Functional Effectors.

Hua L, Zhang Q, Zhu X, Wang R, You Q, Wang L. Hua L, et al. Among authors: zhang q. J Med Chem. 2022 Jun 23;65(12):8091-8112. doi: 10.1021/acs.jmedchem.2c00316. Epub 2022 Jun 10. J Med Chem. 2022. PMID: 35686733 Review.

9

A decade of approved first-in-class small molecule orphan drugs: Achievements, challenges and perspectives.

Gu J, Wu Q, Zhang Q, You Q, Wang L. Gu J, et al. Among authors: zhang q. Eur J Med Chem. 2022 Dec 5;243:114742. doi: 10.1016/j.ejmech.2022.114742. Epub 2022 Sep 9. Eur J Med Chem. 2022. PMID: 36155354 Review.

10

Protein Phosphatase 5-Recruiting Chimeras for Accelerating Apoptosis-Signal-Regulated Kinase 1 Dephosphorylation with Antiproliferative Activity.

Zhang Q, Wu X, Zhang H, Wu Q, Fu M, Hua L, Zhu X, Guo Y, Zhang L, You Q, Wang L. Zhang Q, et al. Among authors: zhang l, zhang h. J Am Chem Soc. 2023 Jan 18;145(2):1118-1128. doi: 10.1021/jacs.2c10759. Epub 2022 Dec 22. J Am Chem Soc. 2023. PMID: 36546850

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