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Increasing Linker Chain Length and Intestinal Stability Enhances Lymphatic Transport and Lymph Node Exposure of Triglyceride Mimetic Prodrugs of a Model Immunomodulator Mycophenolic Acid.
Han S, Quach T, Hu L, Lim SF, Zheng D, Leong NJ, Sharma G, Bonner D, Simpson JS, Trevaskis NL, Porter CJH. Han S, et al. Among authors: trevaskis nl. Mol Pharm. 2023 May 1;20(5):2675-2685. doi: 10.1021/acs.molpharmaceut.3c00099. Epub 2023 Mar 30. Mol Pharm. 2023. PMID: 36996486
Functionalisation of brush polyethylene glycol polymers with specific lipids extends their elimination half-life through association with natural lipid trafficking pathways.
Abdallah M, Lin L, Styles IK, Mörsdorf A, Grace JL, Gracia G, Nowell C, Quinn JF, Landersdorfer CB, Whittaker MR, Trevaskis NL. Abdallah M, et al. Among authors: trevaskis nl. Acta Biomater. 2024 Jan 15;174:191-205. doi: 10.1016/j.actbio.2023.12.002. Epub 2023 Dec 10. Acta Biomater. 2024. PMID: 38086497 Free article.
Systematic Down-Selection of Repurposed Drug Candidates for COVID-19.
MacRaild CA, Mohammed MU, Faheem, Murugesan S, Styles IK, Peterson AL, Kirkpatrick CMJ, Cooper MA, Palombo EA, Simpson MM, Jain HA, Agarwal V, McAuley AJ, Kumar A, Creek DJ, Trevaskis NL, Vasan SS. MacRaild CA, et al. Among authors: trevaskis nl. Int J Mol Sci. 2022 Oct 6;23(19):11851. doi: 10.3390/ijms231911851. Int J Mol Sci. 2022. PMID: 36233149 Free PMC article.
89 results