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Page 1
Effective Therapy Targeting Cytochrome bc1 Prevents Babesia Erythrocytic Development and Protects from Lethal Infection.
Chiu JE, Renard I, Pal AC, Singh P, Vydyam P, Thekkiniath J, Kumar M, Gihaz S, Pou S, Winter RW, Dodean R, Frueh L, Nilsen AC, Riscoe MK, Doggett JS, Mamoun CB. Chiu JE, et al. Among authors: renard i. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0066221. doi: 10.1128/AAC.00662-21. Epub 2021 Aug 17. Antimicrob Agents Chemother. 2021. PMID: 34152821 Free PMC article.
Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone.
Lawres LA, Garg A, Kumar V, Bruzual I, Forquer IP, Renard I, Virji AZ, Boulard P, Rodriguez EX, Allen AJ, Pou S, Wegmann KW, Winter RW, Nilsen A, Mao J, Preston DA, Belperron AA, Bockenstedt LK, Hinrichs DJ, Riscoe MK, Doggett JS, Ben Mamoun C. Lawres LA, et al. Among authors: renard i. J Exp Med. 2016 Jun 27;213(7):1307-18. doi: 10.1084/jem.20151519. Epub 2016 Jun 6. J Exp Med. 2016. PMID: 27270894 Free PMC article.
Evidence for SARS-CoV-2 Spike Protein in the Urine of COVID-19 Patients.
George S, Pal AC, Gagnon J, Timalsina S, Singh P, Vydyam P, Munshi M, Chiu JE, Renard I, Harden CA, Ott IM, Watkins AE, Vogels CBF, Lu P, Tokuyama M, Venkataraman A, Casanovas-Massana A, Wyllie AL, Rao V, Campbell M, Farhadian SF, Grubaugh ND, Dela Cruz CS, Ko AI, Berna Perez AZ, Akaho EH, Moledina DG, Testani J, John AR, Ledizet M, Mamoun CB; and the Yale IMPACT Team. George S, et al. Among authors: renard i. Kidney360. 2021 Apr 14;2(6):924-936. doi: 10.34067/KID.0002172021. eCollection 2021 Jun 24. Kidney360. 2021. PMID: 35373072 Free PMC article.
High-resolution crystal structure and chemical screening reveal pantothenate kinase as a new target for antifungal development.
Gihaz S, Gareiss P, Choi JY, Renard I, Pal AC, Surovsteva Y, Chiu JE, Thekkiniath J, Plummer M, Hungerford W, Montgomery ML, Hosford A, Adams EM, Lightfoot JD, Fox D 3rd, Ojo KK, Staker BL, Fuller K, Ben Mamoun C. Gihaz S, et al. Among authors: renard i. Structure. 2022 Nov 3;30(11):1494-1507.e6. doi: 10.1016/j.str.2022.09.001. Epub 2022 Sep 26. Structure. 2022. PMID: 36167065 Free PMC article.
A kalihinol analog disrupts apicoplast function and vesicular trafficking in P. falciparum malaria.
Chahine Z, Abel S, Hollin T, Barnes GL, Chung JH, Daub ME, Renard I, Choi JY, Vydyam P, Pal A, Alba-Argomaniz M, Banks CAS, Kirkwood J, Saraf A, Camino I, Castaneda P, Cuevas MC, De Mercado-Arnanz J, Fernandez-Alvaro E, Garcia-Perez A, Ibarz N, Viera-Morilla S, Prudhomme J, Joyner CJ, Bei AK, Florens L, Ben Mamoun C, Vanderwal CD, Le Roch KG. Chahine Z, et al. Among authors: renard i. Science. 2024 Sep 27;385(6716):eadm7966. doi: 10.1126/science.adm7966. Epub 2024 Sep 27. Science. 2024. PMID: 39325875
A targeted immunomic approach identifies diagnostic antigens in the human pathogen Babesia microti.
Cornillot E, Dassouli A, Pachikara N, Lawres L, Renard I, Francois C, Randazzo S, Brès V, Garg A, Brancato J, Pazzi JE, Pablo J, Hung C, Teng A, Shandling AD, Huynh VT, Krause PJ, Lepore T, Delbecq S, Hermanson G, Liang X, Williams S, Molina DM, Ben Mamoun C. Cornillot E, et al. Among authors: renard i. Transfusion. 2016 Aug;56(8):2085-99. doi: 10.1111/trf.13640. Epub 2016 May 17. Transfusion. 2016. PMID: 27184823 Free PMC article.
Treatment of Human Babesiosis: Then and Now.
Renard I, Ben Mamoun C. Renard I, et al. Pathogens. 2021 Sep 1;10(9):1120. doi: 10.3390/pathogens10091120. Pathogens. 2021. PMID: 34578153 Free PMC article. Review.
51 results