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New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids.
Rodrigues D, de Souza T, Coyle L, Di Piazza M, Herpers B, Ferreira S, Zhang M, Vappiani J, Sévin DC, Gabor A, Lynch A, Chung SW, Saez-Rodriguez J, Jennen DGJ, Kleinjans JCS, de Kok TM. Rodrigues D, et al. Among authors: lynch a. Arch Toxicol. 2021 Aug;95(8):2691-2718. doi: 10.1007/s00204-021-03092-2. Epub 2021 Jun 20. Arch Toxicol. 2021. PMID: 34151400 Free PMC article.
Mouse organoids as an in vitro tool to study the in vivo intestinal response to cytotoxicants.
Jardi F, Kelly C, Teague C, Fowler-Williams H, Sevin DC, Rodrigues D, Jo H, Ferreira S, Herpers B, Van Heerden M, de Kok T, Pin C, Lynch A, Duckworth CA, De Jonghe S, Lammens L, Pritchard DM. Jardi F, et al. Among authors: lynch a. Arch Toxicol. 2023 Jan;97(1):235-254. doi: 10.1007/s00204-022-03374-3. Epub 2022 Oct 6. Arch Toxicol. 2023. PMID: 36203040
The potential of AB-free kava in enabling tobacco cessation via management of abstinence-related stress and insomnia: study protocol for a randomized clinical trial.
Xing C, Malaty J, Malham MB, Orlando FA, Lynch A, Huo Z, François M, Firpi-Morell R, Fisher CL, Christou DD, Salloum RG. Xing C, et al. Among authors: lynch a. BMC Complement Med Ther. 2024 Dec 21;24(1):422. doi: 10.1186/s12906-024-04722-9. BMC Complement Med Ther. 2024. PMID: 39709468 Free PMC article. Clinical Trial.
Self-organization of the hematopoietic vascular niche and emergent innate immunity on a chip.
Georgescu A, Oved JH, Galarraga JH, Cantrell T, Mehta S, Dulmovits BM, Olson TS, Fattahi P, Wang A, Candarlioglu PL, Muvaffak A, Kim MM, Aydin SA, Seo J, Diffenderfer ES, Lynch A, Worthen GS, Huh DD. Georgescu A, et al. Among authors: lynch a. Cell Stem Cell. 2024 Dec 5;31(12):1847-1864.e6. doi: 10.1016/j.stem.2024.11.003. Cell Stem Cell. 2024. PMID: 39642865
TRPML-1 Dysfunction and Renal Tubulopathy in Mucolipidosis Type IV.
Grieco G, Montefusco S, Nusco E, Capuozzo A, Cervellini F, Polishchuk E, Bishop M, Miele A, D'Apolito L, La Vecchia C, Aurilia M, Schiavo M, Staiano L, Cesana M, Oberman R, Lynch AV, Musolino P, Trepiccione F, Grishchuk Y, Medina DL. Grieco G, et al. Among authors: lynch av. J Am Soc Nephrol. 2024 Dec 4. doi: 10.1681/ASN.0000000567. Online ahead of print. J Am Soc Nephrol. 2024. PMID: 39630508
1,277 results