Hessel E - Search Results

1

Assessment of bacterial exposure on phagocytic capability and surface marker expression of sputum macrophages and neutrophils in COPD patients.

Lea S, Gaskell R, Hall S, Maschera B, Hessel E, Singh D. Lea S, et al. Among authors: hessel e. Clin Exp Immunol. 2021 Oct;206(1):99-109. doi: 10.1111/cei.13638. Epub 2021 Jul 12. Clin Exp Immunol. 2021. PMID: 34143447 Free PMC article. Clinical Trial.

2

The effect of phosphatidylinositol-3 kinase inhibition on matrix metalloproteinase-9 and reactive oxygen species release from chronic obstructive pulmonary disease neutrophils.

Gupta V, Khan A, Higham A, Lemon J, Sriskantharajah S, Amour A, Hessel EM, Southworth T, Singh D. Gupta V, et al. Among authors: hessel em. Int Immunopharmacol. 2016 Jun;35:155-162. doi: 10.1016/j.intimp.2016.03.027. Epub 2016 Apr 16. Int Immunopharmacol. 2016. PMID: 27049289

3

An investigation of the anti-inflammatory effects and a potential biomarker of PI3Kδ inhibition in COPD T cells.

Khan A, Southworth T, Worsley S, Sriskantharajah S, Amour A, Hessel EM, Singh D. Khan A, et al. Clin Exp Pharmacol Physiol. 2017 Sep;44(9):932-940. doi: 10.1111/1440-1681.12784. Clin Exp Pharmacol Physiol. 2017. PMID: 28508433

4

Ampicillin resistance in Haemophilus influenzae from COPD patients in the UK.

Maddi S, Kolsum U, Jackson S, Barraclough R, Maschera B, Simpson KD, Pascal TG, Durviaux S, Hessel EM, Singh D. Maddi S, et al. Int J Chron Obstruct Pulmon Dis. 2017 May 22;12:1507-1518. doi: 10.2147/COPD.S135338. eCollection 2017. Int J Chron Obstruct Pulmon Dis. 2017. PMID: 28579769 Free PMC article.

5

The effects of repeated Toll-like receptors 2 and 4 stimulation in COPD alveolar macrophages.

Lea SR, Reynolds SL, Kaur M, Simpson KD, Hall SR, Hessel EM, Singh D. Lea SR, et al. Int J Chron Obstruct Pulmon Dis. 2018 Mar 2;13:771-780. doi: 10.2147/COPD.S97071. eCollection 2018. Int J Chron Obstruct Pulmon Dis. 2018. PMID: 29535517 Free PMC article.

6

Use of autologous ^99mTechnetium-labelled neutrophils to quantify lung neutrophil clearance in COPD.

Tregay N, Begg M, Cahn A, Farahi N, Povey K, Madhavan S, Simmonds R, Gillett D, Solanki C, Wong A, Maison J, Lennon M, Bradley G, Jarvis E, de Groot M, Wilson F, Babar J, Peters AM, Hessel EM, Chilvers ER. Tregay N, et al. Among authors: hessel em. Thorax. 2019 Jul;74(7):659-666. doi: 10.1136/thoraxjnl-2018-212509. Epub 2019 Jan 23. Thorax. 2019. PMID: 30674586 Free PMC article.

7

Airway host-microbiome interactions in chronic obstructive pulmonary disease.

Wang Z, Maschera B, Lea S, Kolsum U, Michalovich D, Van Horn S, Traini C, Brown JR, Hessel EM, Singh D. Wang Z, et al. Respir Res. 2019 Jun 6;20(1):113. doi: 10.1186/s12931-019-1085-z. Respir Res. 2019. PMID: 31170986 Free PMC article.

8

PI3Kδ inhibition prevents IL33, ILC2s and inflammatory eosinophils in persistent airway inflammation.

Uddin S, Amour A, Lewis DJ, Edwards CD, Williamson MG, Hall S, Lione LA, Hessel EM. Uddin S, et al. BMC Immunol. 2021 Dec 17;22(1):78. doi: 10.1186/s12865-021-00461-5. BMC Immunol. 2021. PMID: 34920698 Free PMC article.

9

Targeting phosphoinositide 3-kinase δ for the treatment of respiratory diseases.

Sriskantharajah S, Hamblin N, Worsley S, Calver AR, Hessel EM, Amour A. Sriskantharajah S, et al. Ann N Y Acad Sci. 2013 Mar;1280:35-9. doi: 10.1111/nyas.12039. Ann N Y Acad Sci. 2013. PMID: 23551101 Review.

10

Acute Respiratory Distress Syndrome Neutrophils Have a Distinct Phenotype and Are Resistant to Phosphoinositide 3-Kinase Inhibition.

Juss JK, House D, Amour A, Begg M, Herre J, Storisteanu DM, Hoenderdos K, Bradley G, Lennon M, Summers C, Hessel EM, Condliffe A, Chilvers ER. Juss JK, et al. Am J Respir Crit Care Med. 2016 Oct 15;194(8):961-973. doi: 10.1164/rccm.201509-1818OC. Am J Respir Crit Care Med. 2016. PMID: 27064380 Free PMC article.

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