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Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA.
Vaisvila R, Ponnaluri VKC, Sun Z, Langhorst BW, Saleh L, Guan S, Dai N, Campbell MA, Sexton BS, Marks K, Samaranayake M, Samuelson JC, Church HE, Tamanaha E, Corrêa IR Jr, Pradhan S, Dimalanta ET, Evans TC Jr, Williams L, Davis TB. Vaisvila R, et al. Genome Res. 2021 Jul;31(7):1280-1289. doi: 10.1101/gr.266551.120. Epub 2021 Jun 17. Genome Res. 2021. PMID: 34140313 Free PMC article.
Nondestructive enzymatic deamination enables single-molecule long-read amplicon sequencing for the determination of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution.
Sun Z, Vaisvila R, Hussong LM, Yan B, Baum C, Saleh L, Samaranayake M, Guan S, Dai N, Corrêa IR Jr, Pradhan S, Davis TB, Evans TC Jr, Ettwiller LM. Sun Z, et al. Among authors: vaisvila r. Genome Res. 2021 Feb;31(2):291-300. doi: 10.1101/gr.265306.120. Epub 2021 Jan 19. Genome Res. 2021. PMID: 33468551 Free PMC article.
Biochemical characterization of a Naegleria TET-like oxygenase and its application in single molecule sequencing of 5-methylcytosine.
Pais JE, Dai N, Tamanaha E, Vaisvila R, Fomenkov AI, Bitinaite J, Sun Z, Guan S, Corrêa IR Jr, Noren CJ, Cheng X, Roberts RJ, Zheng Y, Saleh L. Pais JE, et al. Among authors: vaisvila r. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4316-21. doi: 10.1073/pnas.1417939112. Epub 2015 Mar 23. Proc Natl Acad Sci U S A. 2015. PMID: 25831492 Free PMC article.
Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte.
Hill PWS, Leitch HG, Requena CE, Sun Z, Amouroux R, Roman-Trufero M, Borkowska M, Terragni J, Vaisvila R, Linnett S, Bagci H, Dharmalingham G, Haberle V, Lenhard B, Zheng Y, Pradhan S, Hajkova P. Hill PWS, et al. Among authors: vaisvila r. Nature. 2018 Mar 15;555(7696):392-396. doi: 10.1038/nature25964. Epub 2018 Mar 7. Nature. 2018. PMID: 29513657 Free PMC article.
24 results