Kelkar A - Search Results

1

Local complement factor H protects kidney endothelial cell structure and function.

Mahajan S, Jacob A, Kelkar A, Chang A, Mcskimming D, Neelamegham S, Quigg RJ, Alexander JJ. Mahajan S, et al. Among authors: kelkar a. Kidney Int. 2021 Oct;100(4):824-836. doi: 10.1016/j.kint.2021.05.033. Epub 2021 Jun 15. Kidney Int. 2021. PMID: 34139209

2

Platelet GpIba binding to von Willebrand Factor under fluid shear:contributions of the D′D3-domain, A1-domain flanking peptide and O-linked glycans.

Madabhushi SR, Zhang C, Kelkar A, Dayananda KM, Neelamegham S. Madabhushi SR, et al. Among authors: kelkar a. J Am Heart Assoc. 2014 Oct 23;3(5):e001420. doi: 10.1161/JAHA.114.001420. J Am Heart Assoc. 2014. PMID: 25341886 Free PMC article.

3

The physical spacing between the von Willebrand factor D'D3 and A1 domains regulates platelet adhesion in vitro and in vivo.

Zhang C, Kelkar A, Nasirikenari M, Lau JTY, Sveinsson M, Sharma UC, Pokharel S, Neelamegham S. Zhang C, et al. Among authors: kelkar a. J Thromb Haemost. 2018 Mar;16(3):571-582. doi: 10.1111/jth.13927. Epub 2018 Jan 22. J Thromb Haemost. 2018. PMID: 29251812 Free PMC article.

4

Role of calcium in regulating the intra- and extracellular cleavage of von Willebrand factor by the protease ADAMTS13.

Gogia S, Kelkar A, Zhang C, Dayananda KM, Neelamegham S. Gogia S, et al. Among authors: kelkar a. Blood Adv. 2017 Oct 20;1(23):2063-2074. doi: 10.1182/bloodadvances.2017009027. eCollection 2017 Oct 24. Blood Adv. 2017. PMID: 29296853 Free PMC article.

5

von Willebrand factor self-association is regulated by the shear-dependent unfolding of the A2 domain.

Zhang C, Kelkar A, Neelamegham S. Zhang C, et al. Among authors: kelkar a. Blood Adv. 2019 Apr 9;3(7):957-968. doi: 10.1182/bloodadvances.2018030122. Blood Adv. 2019. PMID: 30936056 Free PMC article.

6

Doxycycline-Dependent Self-Inactivation of CRISPR-Cas9 to Temporally Regulate On- and Off-Target Editing.

Kelkar A, Zhu Y, Groth T, Stolfa G, Stablewski AB, Singhi N, Nemeth M, Neelamegham S. Kelkar A, et al. Mol Ther. 2020 Jan 8;28(1):29-41. doi: 10.1016/j.ymthe.2019.09.006. Epub 2019 Sep 12. Mol Ther. 2020. PMID: 31601489 Free PMC article.

7

A GlycoGene CRISPR-Cas9 lentiviral library to study lectin binding and human glycan biosynthesis pathways.

Zhu Y, Groth T, Kelkar A, Zhou Y, Neelamegham S. Zhu Y, et al. Among authors: kelkar a. Glycobiology. 2021 Apr 1;31(3):173-180. doi: 10.1093/glycob/cwaa074. Glycobiology. 2021. PMID: 32776087 Free PMC article.

8

Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration.

Yang Q, Hughes TA, Kelkar A, Yu X, Cheng K, Park S, Huang WC, Lovell JF, Neelamegham S. Yang Q, et al. Among authors: kelkar a. Elife. 2020 Oct 26;9:e61552. doi: 10.7554/eLife.61552. Elife. 2020. PMID: 33103998 Free PMC article.

9

Forward Genetic Screens of Human Glycosylation Pathways Using the GlycoGene CRISPR Library.

Kelkar A, Groth T, Neelamegham S. Kelkar A, et al. Curr Protoc. 2022 Apr;2(4):e402. doi: 10.1002/cpz1.402. Curr Protoc. 2022. PMID: 35427438 Free PMC article.

10

Role for N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 Spike maturation and viral infectivity.

Yang Q, Kelkar A, Sriram A, Hombu R, Hughes TA, Neelamegham S. Yang Q, et al. Among authors: kelkar a. Sci Adv. 2022 Sep 23;8(38):eabq8678. doi: 10.1126/sciadv.abq8678. Epub 2022 Sep 23. Sci Adv. 2022. PMID: 36149962 Free PMC article.

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