Yang T - Search Results

1

Discovery, Optimization, and Evaluation of Quinazolinone Derivatives with Novel Linkers as Orally Efficacious Phosphoinositide-3-Kinase Delta Inhibitors for Treatment of Inflammatory Diseases.

Liu K, Li D, Zheng W, Shi M, Chen Y, Tang M, Yang T, Zhao M, Deng D, Zhang C, Liu J, Yuan X, Yang Z, Chen L. Liu K, et al. Among authors: yang t, yang z. J Med Chem. 2021 Jul 8;64(13):8951-8970. doi: 10.1021/acs.jmedchem.1c00004. Epub 2021 Jun 17. J Med Chem. 2021. PMID: 34138567

2

Discovery of novel anti-tuberculosis agents with pyrrolo[1,2-a]quinoxaline-based scaffold.

Wang T, Tang Y, Yang Y, An Q, Sang Z, Yang T, Liu P, Zhang T, Deng Y, Luo Y. Wang T, et al. Among authors: yang t, yang y. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2084-2090. doi: 10.1016/j.bmcl.2018.04.043. Epub 2018 May 2. Bioorg Med Chem Lett. 2018. PMID: 29748048

3

Design, synthesis and biological evaluation of novel pyrrole derivatives as potential ClpP1P2 inhibitor against Mycobacterium tuberculosis.

Liu P, Yang Y, Ju Y, Tang Y, Sang Z, Chen L, Yang T, An Q, Zhang T, Luo Y. Liu P, et al. Among authors: yang t, yang y. Bioorg Chem. 2018 Oct;80:422-432. doi: 10.1016/j.bioorg.2018.06.004. Epub 2018 Jun 4. Bioorg Chem. 2018. PMID: 30005200

4

A novel series of napabucasin derivatives as orally active inhibitors of signal transducer and activator of transcription 3 (STAT3).

Li C, Chen C, An Q, Yang T, Sang Z, Yang Y, Ju Y, Tong A, Luo Y. Li C, et al. Among authors: yang t, yang y. Eur J Med Chem. 2019 Jan 15;162:543-554. doi: 10.1016/j.ejmech.2018.10.067. Epub 2018 Nov 1. Eur J Med Chem. 2019. PMID: 30472602

5

Design and synthesis of novel pyrimidine derivatives as potent antitubercular agents.

Liu P, Yang Y, Tang Y, Yang T, Sang Z, Liu Z, Zhang T, Luo Y. Liu P, et al. Among authors: yang t, yang y. Eur J Med Chem. 2019 Feb 1;163:169-182. doi: 10.1016/j.ejmech.2018.11.054. Epub 2018 Nov 26. Eur J Med Chem. 2019. PMID: 30508666

6

Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms.

Yang T, Hu M, Qi W, Yang Z, Tang M, He J, Chen Y, Bai P, Yuan X, Zhang C, Liu K, Lu Y, Xiang M, Chen L. Yang T, et al. Among authors: yang z. J Med Chem. 2019 Nov 27;62(22):10305-10320. doi: 10.1021/acs.jmedchem.9b01348. Epub 2019 Nov 8. J Med Chem. 2019. PMID: 31670517

7

Correction to "Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms".

Yang T, Hu M, Qi W, Yang Z, Tang M, He J, Chen Y, Bai P, Yuan X, Zhang C, Liu K, Lu Y, Xiang M, Chen L. Yang T, et al. Among authors: yang z. J Med Chem. 2020 Feb 13;63(3):1441-1442. doi: 10.1021/acs.jmedchem.0c00025. Epub 2020 Jan 27. J Med Chem. 2020. PMID: 31985218 No abstract available.

8

Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers in Vitro and in Vivo.

Ju Y, He L, Zhou Y, Yang T, Sun K, Song R, Yang Y, Li C, Sang Z, Bao R, Luo Y. Ju Y, et al. Among authors: yang t, yang y. J Med Chem. 2020 Mar 26;63(6):3104-3119. doi: 10.1021/acs.jmedchem.9b01746. Epub 2020 Feb 20. J Med Chem. 2020. PMID: 32031798

9

Repurposed drug candidates for antituberculosis therapy.

An Q, Li C, Chen Y, Deng Y, Yang T, Luo Y. An Q, et al. Among authors: yang t. Eur J Med Chem. 2020 Apr 15;192:112175. doi: 10.1016/j.ejmech.2020.112175. Epub 2020 Feb 25. Eur J Med Chem. 2020. PMID: 32126450 Review.

10

Dihydrofolate reductase inhibitors for use as antimicrobial agents.

He J, Qiao W, An Q, Yang T, Luo Y. He J, et al. Among authors: yang t. Eur J Med Chem. 2020 Jun 1;195:112268. doi: 10.1016/j.ejmech.2020.112268. Epub 2020 Apr 1. Eur J Med Chem. 2020. PMID: 32298876 Review.

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