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Design, Synthesis, In Vitro and In Vivo Characterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in Down Syndrome.
Borgogno M, Savardi A, Manigrasso J, Turci A, Portioli C, Ottonello G, Bertozzi SM, Armirotti A, Contestabile A, Cancedda L, De Vivo M. Borgogno M, et al. Among authors: de vivo m. J Med Chem. 2021 Jul 22;64(14):10203-10229. doi: 10.1021/acs.jmedchem.1c00603. Epub 2021 Jun 17. J Med Chem. 2021. PMID: 34137257 Free PMC article.
Pharmacophore Identification and Scaffold Exploration to Discover Novel, Potent, and Chemically Stable Inhibitors of Acid Ceramidase in Melanoma Cells.
Ortega JA, Arencibia JM, La Sala G, Borgogno M, Bauer I, Bono L, Braccia C, Armirotti A, Girotto S, Ganesan A, De Vivo M. Ortega JA, et al. Among authors: de vivo m. J Med Chem. 2017 Jul 13;60(13):5800-5815. doi: 10.1021/acs.jmedchem.7b00472. Epub 2017 Jun 27. J Med Chem. 2017. PMID: 28603987 Free article.
Design, Synthesis, Dynamic Docking, Biochemical Characterization, and in Vivo Pharmacokinetics Studies of Novel Topoisomerase II Poisons with Promising Antiproliferative Activity.
Arencibia JM, Brindani N, Franco-Ulloa S, Nigro M, Kuriappan JA, Ottonello G, Bertozzi SM, Summa M, Girotto S, Bertorelli R, Armirotti A, De Vivo M. Arencibia JM, et al. Among authors: de vivo m. J Med Chem. 2020 Apr 9;63(7):3508-3521. doi: 10.1021/acs.jmedchem.9b01760. Epub 2020 Mar 30. J Med Chem. 2020. PMID: 32196342 Free PMC article.
295 results