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Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers.
Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP. Rujas E, et al. Among authors: budylowski p. Nat Commun. 2021 Jun 16;12(1):3661. doi: 10.1038/s41467-021-23825-2. Nat Commun. 2021. PMID: 34135340 Free PMC article.
A simple protein-based surrogate neutralization assay for SARS-CoV-2.
Abe KT, Li Z, Samson R, Samavarchi-Tehrani P, Valcourt EJ, Wood H, Budylowski P, Dupuis AP 2nd, Girardin RC, Rathod B, Wang JH, Barrios-Rodiles M, Colwill K, McGeer AJ, Mubareka S, Gommerman JL, Durocher Y, Ostrowski M, McDonough KA, Drebot MA, Drews SJ, Rini JM, Gingras AC. Abe KT, et al. Among authors: budylowski p. JCI Insight. 2020 Oct 2;5(19):e142362. doi: 10.1172/jci.insight.142362. JCI Insight. 2020. PMID: 32870820 Free PMC article.
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients.
Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yue FY, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, McGeer AJ, Gommerman JL, Gingras AC. Isho B, et al. Among authors: budylowski p. Sci Immunol. 2020 Oct 8;5(52):eabe5511. doi: 10.1126/sciimmunol.abe5511. Sci Immunol. 2020. PMID: 33033173 Free PMC article.
Systematic Examination of Antigen-Specific Recall T Cell Responses to SARS-CoV-2 versus Influenza Virus Reveals a Distinct Inflammatory Profile.
Law JC, Koh WH, Budylowski P, Lin J, Yue F, Abe KT, Rathod B, Girard M, Li Z, Rini JM, Mubareka S, McGeer A, Chan AK, Gingras AC, Watts TH, Ostrowski MA. Law JC, et al. Among authors: budylowski p. J Immunol. 2021 Jan 1;206(1):37-50. doi: 10.4049/jimmunol.2001067. Epub 2020 Nov 18. J Immunol. 2021. PMID: 33208459 Free PMC article.
Vapourized hydrogen peroxide decontamination in a hospital setting inactivates SARS-CoV-2 and HCoV-229E without compromising filtration efficiency of unexpired N95 respirators.
Christie-Holmes N, Tyli R, Budylowski P, Guvenc F, Weiner A, Poon B, Speck M, Naugler S, Rainville A, Ghalami A, McCaw S, Hayes S, Mubareka S, Gray-Owen SD, Rotstein OD, Kandel RA, Scott JA. Christie-Holmes N, et al. Among authors: budylowski p. Am J Infect Control. 2021 Oct;49(10):1227-1231. doi: 10.1016/j.ajic.2021.07.012. Epub 2021 Jul 25. Am J Infect Control. 2021. PMID: 34320409 Free PMC article.
Preclinical evaluation of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B.
Liu J, Budylowski P, Samson R, Griffin BD, Babuadze G, Rathod B, Colwill K, Abioye JA, Schwartz JA, Law R, Yip L, Ahn SK, Chau S, Naghibosadat M, Arita Y, Hu Q, Yue FY, Banerjee A, Hardy WR, Mossman K, Mubareka S, Kozak RA, Pollanen MS, Martin Orozco N, Gingras AC, Marcusson EG, Ostrowski MA. Liu J, et al. Among authors: budylowski p. Sci Adv. 2022 Jan 21;8(3):eabj9815. doi: 10.1126/sciadv.abj9815. Epub 2022 Jan 19. Sci Adv. 2022. PMID: 35044832 Free PMC article.
24 results