Gouaux E - Search Results

1

Extracellular loops of the serotonin transporter act as a selectivity filter for drug binding.

Esendir E, Burtscher V, Coleman JA, Zhu R, Gouaux E, Freissmuth M, Sandtner W. Esendir E, et al. Among authors: gouaux e. J Biol Chem. 2021 Jul;297(1):100863. doi: 10.1016/j.jbc.2021.100863. Epub 2021 Jun 9. J Biol Chem. 2021. PMID: 34118233 Free PMC article.

2

X-ray structure of dopamine transporter elucidates antidepressant mechanism.

Penmatsa A, Wang KH, Gouaux E. Penmatsa A, et al. Among authors: gouaux e. Nature. 2013 Nov 7;503(7474):85-90. doi: 10.1038/nature12533. Epub 2013 Sep 15. Nature. 2013. PMID: 24037379 Free PMC article.

3

X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine.

Penmatsa A, Wang KH, Gouaux E. Penmatsa A, et al. Among authors: gouaux e. Nat Struct Mol Biol. 2015 Jun;22(6):506-508. doi: 10.1038/nsmb.3029. Epub 2015 May 11. Nat Struct Mol Biol. 2015. PMID: 25961798 Free PMC article.

4

Neurotransmitter and psychostimulant recognition by the dopamine transporter.

Wang KH, Penmatsa A, Gouaux E. Wang KH, et al. Among authors: gouaux e. Nature. 2015 May 21;521(7552):322-7. doi: 10.1038/nature14431. Epub 2015 May 11. Nature. 2015. PMID: 25970245 Free PMC article.

5

Thermostabilization of the Human Serotonin Transporter in an Antidepressant-Bound Conformation.

Green EM, Coleman JA, Gouaux E. Green EM, et al. Among authors: gouaux e. PLoS One. 2015 Dec 22;10(12):e0145688. doi: 10.1371/journal.pone.0145688. eCollection 2015. PLoS One. 2015. PMID: 26695939 Free PMC article.

6

X-ray structures and mechanism of the human serotonin transporter.

Coleman JA, Green EM, Gouaux E. Coleman JA, et al. Among authors: gouaux e. Nature. 2016 Apr 21;532(7599):334-9. doi: 10.1038/nature17629. Epub 2016 Apr 6. Nature. 2016. PMID: 27049939 Free PMC article.

7

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram.

Coleman JA, Green EM, Gouaux E. Coleman JA, et al. Among authors: gouaux e. J Vis Exp. 2016 Nov 27;(117):54792. doi: 10.3791/54792. J Vis Exp. 2016. PMID: 27929454 Free PMC article.

8

Structural basis for recognition of diverse antidepressants by the human serotonin transporter.

Coleman JA, Gouaux E. Coleman JA, et al. Among authors: gouaux e. Nat Struct Mol Biol. 2018 Feb;25(2):170-175. doi: 10.1038/s41594-018-0026-8. Epub 2018 Jan 29. Nat Struct Mol Biol. 2018. PMID: 29379174 Free PMC article.

9

Thermostabilization and purification of the human dopamine transporter (hDAT) in an inhibitor and allosteric ligand bound conformation.

Navratna V, Tosh DK, Jacobson KA, Gouaux E. Navratna V, et al. Among authors: gouaux e. PLoS One. 2018 Jul 2;13(7):e0200085. doi: 10.1371/journal.pone.0200085. eCollection 2018. PLoS One. 2018. PMID: 29965988 Free PMC article.

10

Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.

Coleman JA, Yang D, Zhao Z, Wen PC, Yoshioka C, Tajkhorshid E, Gouaux E. Coleman JA, et al. Among authors: gouaux e. Nature. 2019 May;569(7754):141-145. doi: 10.1038/s41586-019-1135-1. Epub 2019 Apr 24. Nature. 2019. PMID: 31019304 Free PMC article.

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