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The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson's disease brain as revealed by multicolor STED microscopy.
Moors TE, Maat CA, Niedieker D, Mona D, Petersen D, Timmermans-Huisman E, Kole J, El-Mashtoly SF, Spycher L, Zago W, Barbour R, Mundigl O, Kaluza K, Huber S, Hug MN, Kremer T, Ritter M, Dziadek S, Geurts JJG, Gerwert K, Britschgi M, van de Berg WDJ. Moors TE, et al. Among authors: spycher l. Acta Neuropathol. 2021 Sep;142(3):423-448. doi: 10.1007/s00401-021-02329-9. Epub 2021 Jun 11. Acta Neuropathol. 2021. PMID: 34115198 Free PMC article.
Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies.
Moors TE, Mona D, Luehe S, Duran-Pacheco G, Spycher L, Mundigl O, Kaluza K, Huber S, Hug MN, Kremer T, Ritter M, Dziadek S, Dernick G, van de Berg WDJ, Britschgi M. Moors TE, et al. Among authors: spycher l. Acta Neuropathol Commun. 2022 Jun 3;10(1):82. doi: 10.1186/s40478-022-01382-z. Acta Neuropathol Commun. 2022. PMID: 35659116 Free PMC article.
Specific immune modulation of experimental colitis drives enteric alpha-synuclein accumulation and triggers age-related Parkinson-like brain pathology.
Grathwohl S, Quansah E, Maroof N, Steiner JA, Spycher L, Benmansour F, Duran-Pacheco G, Siebourg-Polster J, Oroszlan-Szovik K, Remy H, Haenggi M, Stawiski M, Selhausen M, Mailver P, Wolfert A, Emrich T, Madaj Z, Su A, Escobar Galvis ML, Mueller C, Herrmann A, Brundin P, Britschgi M. Grathwohl S, et al. Among authors: spycher l. Free Neuropathol. 2021 May 18;2:2-13. doi: 10.17879/freeneuropathology-2021-3326. eCollection 2021 Jan. Free Neuropathol. 2021. PMID: 37284635 Free PMC article.
Three-Dimensional Imaging of Biological Tissue by Cryo X-Ray Ptychography.
Shahmoradian SH, Tsai EHR, Diaz A, Guizar-Sicairos M, Raabe J, Spycher L, Britschgi M, Ruf A, Stahlberg H, Holler M. Shahmoradian SH, et al. Among authors: spycher l. Sci Rep. 2017 Jul 24;7(1):6291. doi: 10.1038/s41598-017-05587-4. Sci Rep. 2017. PMID: 28740127 Free PMC article.