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The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia.
Maat H, Atsma TJ, Hogeling SM, Rodríguez López A, Jaques J, Olthuis M, de Vries MP, Gravesteijn C, Brouwers-Vos AZ, van der Meer N, Datema S, Salzbrunn J, Huls G, Baas R, Martens JHA, van den Boom V, Schuringa JJ. Maat H, et al. Among authors: rodriguez lopez a. iScience. 2021 Apr 16;24(5):102435. doi: 10.1016/j.isci.2021.102435. eCollection 2021 May 21. iScience. 2021. PMID: 34113809 Free PMC article.
Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis.
van den Boom V, Maat H, Geugien M, Rodríguez López A, Sotoca AM, Jaques J, Brouwers-Vos AZ, Fusetti F, Groen RW, Yuan H, Martens AC, Stunnenberg HG, Vellenga E, Martens JH, Schuringa JJ. van den Boom V, et al. Among authors: rodriguez lopez a. Cell Rep. 2016 Jan 12;14(2):332-46. doi: 10.1016/j.celrep.2015.12.034. Epub 2015 Dec 31. Cell Rep. 2016. PMID: 26748712 Free article.
Evaluation of the role of metabolizing enzymes and transporter variants in ezetimibe pharmacokinetics.
González-Iglesias E, Ochoa D, Navares-Gómez M, Zubiaur P, Aldama M, de la Torre T, Ríos-Rodríguez ML, Soria-Chacartegui P, Rodríguez-Lopez A, Abad-Santos F, Novalbos J. González-Iglesias E, et al. Among authors: rodriguez lopez a. Front Pharmacol. 2024 Oct 17;15:1414059. doi: 10.3389/fphar.2024.1414059. eCollection 2024. Front Pharmacol. 2024. PMID: 39484171 Free PMC article.
An Investigational Study on the Role of CYP2D6, CYP3A4 and UGTs Genetic Variation on Fesoterodine Pharmacokinetics in Young Healthy Volunteers.
Rodríguez-Lopez A, Ochoa D, Soria-Chacartegui P, Martín-Vilchez S, Navares-Gómez M, González-Iglesias E, Luquero-Bueno S, Román M, Mejía-Abril G, Abad-Santos F. Rodríguez-Lopez A, et al. Pharmaceuticals (Basel). 2024 Sep 19;17(9):1236. doi: 10.3390/ph17091236. Pharmaceuticals (Basel). 2024. PMID: 39338398 Free PMC article.
Performance comparison of a previously validated microhaplotype panel and a forensic STR panel for DNA mixture analysis.
González-Bao J, Mosquera-Miguel A, Casanova-Adán L, Ambroa-Conde A, Ruiz-Ramírez J, Cabrejas-Olalla A, Boullón-Cassau M, Freire-Aradas A, Rodríguez-López A, Roth C, Lagacé R, Phillips C, Lareu MV, de la Puente M. González-Bao J, et al. Among authors: rodriguez lopez a. Forensic Sci Int Genet. 2025 Jan;74:103144. doi: 10.1016/j.fsigen.2024.103144. Epub 2024 Sep 7. Forensic Sci Int Genet. 2025. PMID: 39270547 Free article.
Genetic Variation in CYP2D6, UGT1A4, SLC6A2 and SLCO1B1 Alters the Pharmacokinetics and Safety of Mirabegron.
Soria-Chacartegui P, Cendoya-Ramiro P, González-Iglesias E, Martín-Vílchez S, Rodríguez-Lopez A, Mejía-Abril G, Román M, Luquero-Bueno S, Ochoa D, Abad-Santos F. Soria-Chacartegui P, et al. Among authors: rodriguez lopez a. Pharmaceutics. 2024 Aug 17;16(8):1077. doi: 10.3390/pharmaceutics16081077. Pharmaceutics. 2024. PMID: 39204422 Free PMC article.
SLCO1B1 and ABCG2 genotype-informed phenotypes are related to variation in ramipril exposure.
Abbes H, Zubiaur P, Soria-Chacartegui P, de la Torre T, Villapalos-García G, Candau C, Rodríguez-Lopez A, González-Iglesias E, Aldama M, Navares-Gomez M, Omezzine A, Ochoa D, Abad-Santos F. Abbes H, et al. Among authors: rodriguez lopez a. Basic Clin Pharmacol Toxicol. 2024 Sep;135(3):295-307. doi: 10.1111/bcpt.14046. Epub 2024 Jul 16. Basic Clin Pharmacol Toxicol. 2024. PMID: 39011815 Clinical Trial.
116 results