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BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage.
Vohhodina J, Goehring LJ, Liu B, Kong Q, Botchkarev VV Jr, Huynh M, Liu Z, Abderazzaq FO, Clark AP, Ficarro SB, Marto JA, Hatchi E, Livingston DM. Vohhodina J, et al. Among authors: huynh m. Nat Commun. 2021 Jun 10;12(1):3542. doi: 10.1038/s41467-021-23716-6. Nat Commun. 2021. PMID: 34112789 Free PMC article.
MTH1 as a Chemotherapeutic Target: The Elephant in the Room.
Samaranayake GJ, Huynh M, Rai P. Samaranayake GJ, et al. Among authors: huynh m. Cancers (Basel). 2017 May 8;9(5):47. doi: 10.3390/cancers9050047. Cancers (Basel). 2017. PMID: 28481306 Free PMC article. Review.
The Existence of MTH1-independent 8-oxodGTPase Activity in Cancer Cells as a Compensatory Mechanism against On-target Effects of MTH1 Inhibitors.
Samaranayake GJ, Troccoli CI, Zhang L, Huynh M, Jayaraj CJ, Ji D, McPherson L, Onishi Y, Nguyen DM, Robbins DJ, Karbaschi M, Cooke MS, Barrientos A, Kool ET, Rai P. Samaranayake GJ, et al. Among authors: huynh m. Mol Cancer Ther. 2020 Feb;19(2):432-446. doi: 10.1158/1535-7163.MCT-19-0437. Epub 2019 Nov 19. Mol Cancer Ther. 2020. PMID: 31744893 Free PMC article.
669 results