Okuda Y - Search Results

1

Efficacy and safety of esaxerenone (CS-3150) in Japanese patients with type 2 diabetes and macroalbuminuria: a multicenter, single-arm, open-label phase III study.

Ito S, Kashihara N, Shikata K, Nangaku M, Wada T, Okuda Y, Sawanobori T. Ito S, et al. Among authors: okuda y. Clin Exp Nephrol. 2021 Oct;25(10):1070-1078. doi: 10.1007/s10157-021-02075-y. Epub 2021 Jun 10. Clin Exp Nephrol. 2021. PMID: 34110524 Free PMC article. Clinical Trial.

2

Efficacy and safety of esaxerenone (CS-3150) for the treatment of essential hypertension: a phase 2 randomized, placebo-controlled, double-blind study.

Ito S, Itoh H, Rakugi H, Okuda Y, Yamakawa S. Ito S, et al. Among authors: okuda y. J Hum Hypertens. 2019 Jul;33(7):542-551. doi: 10.1038/s41371-019-0207-x. Epub 2019 May 21. J Hum Hypertens. 2019. PMID: 31113987 Free PMC article. Clinical Trial.

3

Efficacy and safety of dosage-escalation of low-dosage esaxerenone added to a RAS inhibitor in hypertensive patients with type 2 diabetes and albuminuria: a single-arm, open-label study.

Itoh H, Ito S, Rakugi H, Okuda Y, Nishioka S. Itoh H, et al. Among authors: okuda y. Hypertens Res. 2019 Oct;42(10):1572-1581. doi: 10.1038/s41440-019-0270-2. Epub 2019 Jun 25. Hypertens Res. 2019. PMID: 31239535 Free PMC article.

4

Efficacy and Safety of Esaxerenone (CS-3150) for the Treatment of Type 2 Diabetes with Microalbuminuria: A Randomized, Double-Blind, Placebo-Controlled, Phase II Trial.

Ito S, Shikata K, Nangaku M, Okuda Y, Sawanobori T. Ito S, et al. Among authors: okuda y. Clin J Am Soc Nephrol. 2019 Aug 7;14(8):1161-1172. doi: 10.2215/CJN.14751218. Epub 2019 Jun 27. Clin J Am Soc Nephrol. 2019. PMID: 31248950 Free PMC article. Clinical Trial.

5

Long-term phase 3 study of esaxerenone as mono or combination therapy with other antihypertensive drugs in patients with essential hypertension.

Rakugi H, Ito S, Itoh H, Okuda Y, Yamakawa S. Rakugi H, et al. Among authors: okuda y. Hypertens Res. 2019 Dec;42(12):1932-1941. doi: 10.1038/s41440-019-0314-7. Epub 2019 Sep 25. Hypertens Res. 2019. PMID: 31554937 Free PMC article. Clinical Trial.

6

Double-Blind Randomized Phase 3 Study Comparing Esaxerenone (CS-3150) and Eplerenone in Patients With Essential Hypertension (ESAX-HTN Study).

Ito S, Itoh H, Rakugi H, Okuda Y, Yoshimura M, Yamakawa S. Ito S, et al. Among authors: okuda y. Hypertension. 2020 Jan;75(1):51-58. doi: 10.1161/HYPERTENSIONAHA.119.13569. Epub 2019 Dec 2. Hypertension. 2020. PMID: 31786983 Free article. Clinical Trial.

7

Effect of the Nonsteroidal Mineralocorticoid Receptor Blocker, Esaxerenone, on Nocturnal Hypertension: A Post Hoc Analysis of the ESAX-HTN Study.

Kario K, Ito S, Itoh H, Rakugi H, Okuda Y, Yoshimura M, Yamakawa S. Kario K, et al. Among authors: okuda y. Am J Hypertens. 2021 May 22;34(5):540-551. doi: 10.1093/ajh/hpaa155. Am J Hypertens. 2021. PMID: 33165570 Free PMC article. Clinical Trial.

8

Efficacy and safety of esaxerenone (CS-3150), a newly available nonsteroidal mineralocorticoid receptor blocker, in hypertensive patients with primary aldosteronism.

Satoh F, Ito S, Itoh H, Rakugi H, Shibata H, Ichihara A, Omura M, Takahashi K, Okuda Y, Iijima S. Satoh F, et al. Among authors: okuda y. Hypertens Res. 2021 Apr;44(4):464-472. doi: 10.1038/s41440-020-00570-5. Epub 2020 Nov 16. Hypertens Res. 2021. PMID: 33199881 Free PMC article.

9

Esaxerenone (CS-3150) in Patients with Type 2 Diabetes and Microalbuminuria (ESAX-DN): Phase 3 Randomized Controlled Clinical Trial.

Ito S, Kashihara N, Shikata K, Nangaku M, Wada T, Okuda Y, Sawanobori T. Ito S, et al. Among authors: okuda y. Clin J Am Soc Nephrol. 2020 Dec 7;15(12):1715-1727. doi: 10.2215/CJN.06870520. Epub 2020 Nov 25. Clin J Am Soc Nephrol. 2020. PMID: 33239409 Free PMC article. Clinical Trial.

10

Antihypertensive effects and safety of esaxerenone in patients with moderate kidney dysfunction.

Ito S, Itoh H, Rakugi H, Okuda Y, Iijima S. Ito S, et al. Among authors: okuda y. Hypertens Res. 2021 May;44(5):489-497. doi: 10.1038/s41440-020-00585-y. Epub 2020 Dec 16. Hypertens Res. 2021. PMID: 33323991 Free PMC article.

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