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Senolytics reduce coronavirus-related mortality in old mice.
Camell CD, Yousefzadeh MJ, Zhu Y, Prata LGPL, Huggins MA, Pierson M, Zhang L, O'Kelly RD, Pirtskhalava T, Xun P, Ejima K, Xue A, Tripathi U, Espindola-Netto JM, Giorgadze N, Atkinson EJ, Inman CL, Johnson KO, Cholensky SH, Carlson TW, LeBrasseur NK, Khosla S, O'Sullivan MG, Allison DB, Jameson SC, Meves A, Li M, Prakash YS, Chiarella SE, Hamilton SE, Tchkonia T, Niedernhofer LJ, Kirkland JL, Robbins PD. Camell CD, et al. Among authors: tchkonia t. Science. 2021 Jul 16;373(6552):eabe4832. doi: 10.1126/science.abe4832. Epub 2021 Jun 8. Science. 2021. PMID: 34103349 Free PMC article.
Adipogenesis and aging: does aging make fat go MAD?
Kirkland JL, Tchkonia T, Pirtskhalava T, Han J, Karagiannides I. Kirkland JL, et al. Among authors: tchkonia t. Exp Gerontol. 2002 Jun;37(6):757-67. doi: 10.1016/s0531-5565(02)00014-1. Exp Gerontol. 2002. PMID: 12175476 Review.
Induction of colitis causes inflammatory responses in fat depots: evidence for substance P pathways in human mesenteric preadipocytes.
Karagiannides I, Kokkotou E, Tansky M, Tchkonia T, Giorgadze N, O'Brien M, Leeman SE, Kirkland JL, Pothoulakis C. Karagiannides I, et al. Among authors: tchkonia t. Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5207-12. doi: 10.1073/pnas.0600821103. Epub 2006 Mar 20. Proc Natl Acad Sci U S A. 2006. PMID: 16549770 Free PMC article.
Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity.
Guo W, Pirtskhalava T, Tchkonia T, Xie W, Thomou T, Han J, Wang T, Wong S, Cartwright A, Hegardt FG, Corkey BE, Kirkland JL. Guo W, et al. Among authors: tchkonia t. Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1041-51. doi: 10.1152/ajpendo.00557.2006. Epub 2006 Dec 5. Am J Physiol Endocrinol Metab. 2007. PMID: 17148751 Free article.
Aging, depot origin, and preadipocyte gene expression.
Cartwright MJ, Schlauch K, Lenburg ME, Tchkonia T, Pirtskhalava T, Cartwright A, Thomou T, Kirkland JL. Cartwright MJ, et al. Among authors: tchkonia t. J Gerontol A Biol Sci Med Sci. 2010 Mar;65(3):242-51. doi: 10.1093/gerona/glp213. Epub 2010 Jan 27. J Gerontol A Biol Sci Med Sci. 2010. PMID: 20106964 Free PMC article.
Sex- and depot-dependent differences in adipogenesis in normal-weight humans.
Tchoukalova YD, Koutsari C, Votruba SB, Tchkonia T, Giorgadze N, Thomou T, Kirkland JL, Jensen MD. Tchoukalova YD, et al. Among authors: tchkonia t. Obesity (Silver Spring). 2010 Oct;18(10):1875-80. doi: 10.1038/oby.2010.56. Epub 2010 Mar 18. Obesity (Silver Spring). 2010. PMID: 20300084 Free PMC article.
202 results