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Senolytics reduce coronavirus-related mortality in old mice.
Camell CD, Yousefzadeh MJ, Zhu Y, Prata LGPL, Huggins MA, Pierson M, Zhang L, O'Kelly RD, Pirtskhalava T, Xun P, Ejima K, Xue A, Tripathi U, Espindola-Netto JM, Giorgadze N, Atkinson EJ, Inman CL, Johnson KO, Cholensky SH, Carlson TW, LeBrasseur NK, Khosla S, O'Sullivan MG, Allison DB, Jameson SC, Meves A, Li M, Prakash YS, Chiarella SE, Hamilton SE, Tchkonia T, Niedernhofer LJ, Kirkland JL, Robbins PD. Camell CD, et al. Among authors: niedernhofer lj. Science. 2021 Jul 16;373(6552):eabe4832. doi: 10.1126/science.abe4832. Epub 2021 Jun 8. Science. 2021. PMID: 34103349 Free PMC article.
Premature aging-related peripheral neuropathy in a mouse model of progeria.
Goss JR, Stolz DB, Robinson AR, Zhang M, Arbujas N, Robbins PD, Glorioso JC, Niedernhofer LJ. Goss JR, et al. Among authors: niedernhofer lj. Mech Ageing Dev. 2011 Aug;132(8-9):437-42. doi: 10.1016/j.mad.2011.04.010. Epub 2011 May 11. Mech Ageing Dev. 2011. PMID: 21596054 Free PMC article.
NF-κB in Aging and Disease.
Tilstra JS, Clauson CL, Niedernhofer LJ, Robbins PD. Tilstra JS, et al. Among authors: niedernhofer lj. Aging Dis. 2011 Dec;2(6):449-65. Epub 2011 Dec 2. Aging Dis. 2011. PMID: 22396894 Free PMC article.
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Zhu Y, Tchkonia T, Pirtskhalava T, Gower AC, Ding H, Giorgadze N, Palmer AK, Ikeno Y, Hubbard GB, Lenburg M, O'Hara SP, LaRusso NF, Miller JD, Roos CM, Verzosa GC, LeBrasseur NK, Wren JD, Farr JN, Khosla S, Stout MB, McGowan SJ, Fuhrmann-Stroissnigg H, Gurkar AU, Zhao J, Colangelo D, Dorronsoro A, Ling YY, Barghouthy AS, Navarro DC, Sano T, Robbins PD, Niedernhofer LJ, Kirkland JL. Zhu Y, et al. Among authors: niedernhofer lj. Aging Cell. 2015 Aug;14(4):644-58. doi: 10.1111/acel.12344. Epub 2015 Apr 22. Aging Cell. 2015. PMID: 25754370 Free PMC article.
196 results