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Page 1
Scientific and regulatory evaluation of mechanistic in silico drug and disease models in drug development: Building model credibility.
Musuamba FT, Skottheim Rusten I, Lesage R, Russo G, Bursi R, Emili L, Wangorsch G, Manolis E, Karlsson KE, Kulesza A, Courcelles E, Boissel JP, Rousseau CF, Voisin EM, Alessandrello R, Curado N, Dall'ara E, Rodriguez B, Pappalardo F, Geris L. Musuamba FT, et al. CPT Pharmacometrics Syst Pharmacol. 2021 Aug;10(8):804-825. doi: 10.1002/psp4.12669. Epub 2021 Jul 13. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34102034 Free PMC article.
Commentary on the MID3 Good Practices Paper.
Manolis E, Brogren J, Cole S, Hay JL, Nordmark A, Karlsson KE, Lentz F, Benda N, Wangorsch G, Pons G, Zhao W, Gigante V, Serone F, Standing JF, Dokoumetzidis A, Vakkilainen J, van den Heuvel M, Mangas Sanjuan V, Taminiau J, Kerwash E, Khan D, Musuamba FT, Skottheim Rusten I; EMA Modelling and Simulation Working Group. Manolis E, et al. Among authors: musuamba ft. CPT Pharmacometrics Syst Pharmacol. 2017 Jul;6(7):416-417. doi: 10.1002/psp4.12223. Epub 2017 Jul 22. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 28653481 Free PMC article.
Verifying and Validating Quantitative Systems Pharmacology and In Silico Models in Drug Development: Current Needs, Gaps, and Challenges.
Musuamba FT, Bursi R, Manolis E, Karlsson K, Kulesza A, Courcelles E, Boissel JP, Lesage R, Crozatier C, Voisin EM, Rousseau CF, Marchal T, Alessandrello R, Geris L. Musuamba FT, et al. CPT Pharmacometrics Syst Pharmacol. 2020 Apr;9(4):195-197. doi: 10.1002/psp4.12504. Epub 2020 Apr 1. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 32237207 Free PMC article. No abstract available.
Advanced Methods for Dose and Regimen Finding During Drug Development: Summary of the EMA/EFPIA Workshop on Dose Finding (London 4-5 December 2014).
Musuamba FT, Manolis E, Holford N, Cheung S, Friberg LE, Ogungbenro K, Posch M, Yates J, Berry S, Thomas N, Corriol-Rohou S, Bornkamp B, Bretz F, Hooker AC, Van der Graaf PH, Standing JF, Hay J, Cole S, Gigante V, Karlsson K, Dumortier T, Benda N, Serone F, Das S, Brochot A, Ehmann F, Hemmings R, Rusten IS. Musuamba FT, et al. CPT Pharmacometrics Syst Pharmacol. 2017 Jul;6(7):418-429. doi: 10.1002/psp4.12196. Epub 2017 Jul 19. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 28722322 Free PMC article.
Model informed dosing of hydroxycholoroquine in COVID-19 patients: Learnings from the recent experience, remaining uncertainties and gaps.
Thémans P, Dauby N, Schrooyen L, Lebout F, Delforge M, Nasreddine R, Libois A, Payen MC, Konopnicki D, Wuillaume F, Lescrainier C, Verlinden V, Dogné JM, Hamdani J, Musuamba FT. Thémans P, et al. Among authors: musuamba ft. Br J Clin Pharmacol. 2021 Feb;87(2):674-682. doi: 10.1111/bcp.14436. Epub 2020 Jul 19. Br J Clin Pharmacol. 2021. PMID: 32559820 Free article.
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