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Specific targeting of the KRAS mutational landscape in myeloma as a tool to unveil the elicited antitumor activity.
Sacco A, Federico C, Todoerti K, Ziccheddu B, Palermo V, Giacomini A, Ravelli C, Maccarinelli F, Bianchi G, Belotti A, Ribolla R, Favasuli V, Revenko AS, Macleod AR, Willis B, Cai H, Hauser J, Rooney C, Willis SE, Martin PL, Staniszewska A, Ambrose H, Hanson L, Cattaneo C, Tucci A, Rossi G, Ronca R, Neri A, Mitola S, Bolli N, Presta M, Moschetta M, Ross S, Roccaro AM. Sacco A, et al. Among authors: palermo v. Blood. 2021 Nov 4;138(18):1705-1720. doi: 10.1182/blood.2020010572. Blood. 2021. PMID: 34077955 Free PMC article.
SHP2's gain-of-function in Werner syndrome causes childhood disease onset likely resulting from negative genetic interaction.
Priolo M, Palermo V, Aiello F, Ciolfi A, Pannone L, Muto V, Motta M, Mancini C, Radio FC, Niceta M, Leoni C, Pintomalli L, Carrozzo R, Rajola G, Mammì C, Zampino G, Martinelli S, Dallapiccola B, Pichierri P, Tartaglia M. Priolo M, et al. Among authors: palermo v. Clin Genet. 2022 Jul;102(1):12-21. doi: 10.1111/cge.14140. Epub 2022 Apr 17. Clin Genet. 2022. PMID: 35396703
R-Loop-Associated Genomic Instability and Implication of WRN and WRNIP1.
Marabitti V, Valenzisi P, Lillo G, Malacaria E, Palermo V, Pichierri P, Franchitto A. Marabitti V, et al. Among authors: palermo v. Int J Mol Sci. 2022 Jan 28;23(3):1547. doi: 10.3390/ijms23031547. Int J Mol Sci. 2022. PMID: 35163467 Free PMC article. Review.
CDK1 phosphorylates WRN at collapsed replication forks.
Palermo V, Rinalducci S, Sanchez M, Grillini F, Sommers JA, Brosh RM Jr, Zolla L, Franchitto A, Pichierri P. Palermo V, et al. Nat Commun. 2016 Sep 16;7:12880. doi: 10.1038/ncomms12880. Nat Commun. 2016. PMID: 27634057 Free PMC article.
179 results