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Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations.
Nakajima S, Watashi K, Kato T, Muramatsu M, Wakita T, Tamura N, Hattori SI, Maeda K, Mitsuya H, Yasutake Y, Toyoda T. Nakajima S, et al. Among authors: yasutake y. J Virol. 2021 Jul 26;95(16):e0240120. doi: 10.1128/JVI.02401-20. Epub 2021 Jul 26. J Virol. 2021. PMID: 34076480 Free PMC article.
ETV-TP is likely to interact primarily with HBV RT M171 prior to final accommodation at the deoxynucleoside triphosphate (dNTP) binding site (Y. Yasutake, S. Hattori, H. Hayashi, K. Matsuda, et al., Sci Rep 8:1624, 2018, https://doi.org/10.1038/s41598-018-19602-9). …
ETV-TP is likely to interact primarily with HBV RT M171 prior to final accommodation at the deoxynucleoside triphosphate (dNTP) binding site …
Structure of the HIV-1 reverse transcriptase Q151M mutant: insights into the inhibitor resistance of HIV-1 reverse transcriptase and the structure of the nucleotide-binding pocket of Hepatitis B virus polymerase.
Nakamura A, Tamura N, Yasutake Y. Nakamura A, et al. Among authors: yasutake y. Acta Crystallogr F Struct Biol Commun. 2015 Nov;71(Pt 11):1384-90. doi: 10.1107/S2053230X15017896. Epub 2015 Oct 23. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 26527265 Free PMC article.
Active-site deformation in the structure of HIV-1 RT with HBV-associated septuple amino acid substitutions rationalizes the differential susceptibility of HIV-1 and HBV against 4'-modified nucleoside RT inhibitors.
Yasutake Y, Hattori SI, Tamura N, Matsuda K, Kohgo S, Maeda K, Mitsuya H. Yasutake Y, et al. Biochem Biophys Res Commun. 2019 Feb 19;509(4):943-948. doi: 10.1016/j.bbrc.2019.01.026. Epub 2019 Jan 14. Biochem Biophys Res Commun. 2019. PMID: 30648556
Correction for Nakajima et al., "Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations".
Nakajima S, Watashi K, Kato T, Muramatsu M, Wakita T, Tamura N, Hattori S-i, Maeda K, Mitsuya H, Yasutake Y, Toyoda T. Nakajima S, et al. Among authors: yasutake y. J Virol. 2024 Mar 19;98(3):e0182323. doi: 10.1128/jvi.01823-23. Epub 2024 Feb 2. J Virol. 2024. PMID: 38305151 Free PMC article. No abstract available.
81 results