Al Nakeeb M - Search Results

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An antibody-drug conjugate with intracellular drug release properties showing specific cytotoxicity against CD7-positive cells.

Zhang J, Jain A, Milhas S, Williamson DJ, Mysliwy J, Lodge A, Thirlway J, Al Nakeeb M, Miller A, Rabbitts TH. Zhang J, et al. Among authors: al nakeeb m. Leuk Res. 2021 Sep;108:106626. doi: 10.1016/j.leukres.2021.106626. Epub 2021 May 18. Leuk Res. 2021. PMID: 34062328 Free PMC article.

Introduction of a non-natural amino acid into a nonribosomal peptide antibiotic by modification of adenylation domain specificity.

Thirlway J, Lewis R, Nunns L, Al Nakeeb M, Styles M, Struck AW, Smith CP, Micklefield J. Thirlway J, et al. Among authors: al nakeeb m. Angew Chem Int Ed Engl. 2012 Jul 16;51(29):7181-4. doi: 10.1002/anie.201202043. Epub 2012 Jun 18. Angew Chem Int Ed Engl. 2012. PMID: 22711659

Biosynthesis of the (2S,3R)-3-methyl glutamate residue of nonribosomal lipopeptides.

Milne C, Powell A, Jim J, Al Nakeeb M, Smith CP, Micklefield J. Milne C, et al. Among authors: al nakeeb m. J Am Chem Soc. 2006 Aug 30;128(34):11250-9. doi: 10.1021/ja062960c. J Am Chem Soc. 2006. PMID: 16925444

Precursor-directed biosynthesis of nonribosomal lipopeptides with modified glutamate residues.

Powell A, Al Nakeeb M, Wilkinson B, Micklefield J. Powell A, et al. Among authors: al nakeeb m. Chem Commun (Camb). 2007 Jul 14;(26):2683-5. doi: 10.1039/b706224a. Epub 2007 May 29. Chem Commun (Camb). 2007. PMID: 17594019

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