Liu J - Search Results

1

Dasatinib-SIK2 Binding Elucidated by Homology Modeling, Molecular Docking, and Dynamics Simulations.

Shi M, Wang L, Li P, Liu J, Chen L, Xu D. Shi M, et al. Among authors: liu j. ACS Omega. 2021 Apr 15;6(16):11025-11038. doi: 10.1021/acsomega.1c00947. eCollection 2021 Apr 27. ACS Omega. 2021. PMID: 34056256 Free PMC article.

2

Exploring the stability of inhibitor binding to SIK2 using molecular dynamics simulation and binding free energy calculation.

Shi M, Zhao M, Wang L, Liu K, Li P, Liu J, Cai X, Chen L, Xu D. Shi M, et al. Among authors: liu k, liu j. Phys Chem Chem Phys. 2021 Jun 16;23(23):13216-13227. doi: 10.1039/d1cp00717c. Phys Chem Chem Phys. 2021. PMID: 34086021

3

Discovery, Optimization, and Evaluation of Quinazolinone Derivatives with Novel Linkers as Orally Efficacious Phosphoinositide-3-Kinase Delta Inhibitors for Treatment of Inflammatory Diseases.

Liu K, Li D, Zheng W, Shi M, Chen Y, Tang M, Yang T, Zhao M, Deng D, Zhang C, Liu J, Yuan X, Yang Z, Chen L. Liu K, et al. Among authors: liu j. J Med Chem. 2021 Jul 8;64(13):8951-8970. doi: 10.1021/acs.jmedchem.1c00004. Epub 2021 Jun 17. J Med Chem. 2021. PMID: 34138567

4

Discovery of a Series of Hydroxamic Acid-Based Microtubule Destabilizing Agents with Potent Antitumor Activity.

Yang L, Zhang W, Qiu Q, Su Z, Tang M, Bai P, Si W, Zhu Z, Liu Y, Yang J, Kuang S, Liu J, Yan W, Shi M, Ye H, Yang Z, Chen L. Yang L, et al. Among authors: liu j, liu y. J Med Chem. 2021 Oct 28;64(20):15379-15401. doi: 10.1021/acs.jmedchem.1c01451. Epub 2021 Oct 14. J Med Chem. 2021. PMID: 34648295

5

Structure-Based Design and Synthesis of N-Substituted 3-Amino-β-Carboline Derivatives as Potent αβ-Tubulin Degradation Agents.

Li Y, Liu Y, Zhu Z, Yan W, Zhang C, Yang Z, Bai P, Tang M, Shi M, He W, Fu S, Liu J, Han K, Li J, Xie L, Ye H, Yang J, Chen L. Li Y, et al. Among authors: liu j, liu y. J Med Chem. 2022 Feb 10;65(3):2675-2693. doi: 10.1021/acs.jmedchem.1c02159. Epub 2022 Jan 27. J Med Chem. 2022. PMID: 35084853

6

Design, synthesis and biological evaluation of novel FAK inhibitors with better selectivity over IR than TAE226.

Chen T, Liu Y, Liu J, Tang M, Huang H, Bai C, Si W, Yang T, Yuan X, Wen Y, Chen L. Chen T, et al. Among authors: liu j, liu y. Bioorg Chem. 2022 Jul;124:105790. doi: 10.1016/j.bioorg.2022.105790. Epub 2022 Apr 6. Bioorg Chem. 2022. PMID: 35452915

7

Discovery of Potent and Selective Receptor-Interacting Serine/Threonine Protein Kinase 2 (RIPK2) Inhibitors for the Treatment of Inflammatory Bowel Diseases (IBDs).

Yuan X, Chen Y, Tang M, Wei Y, Shi M, Yang Y, Zhou Y, Yang T, Liu J, Liu K, Deng D, Zhang C, Chen L. Yuan X, et al. Among authors: liu k, liu j. J Med Chem. 2022 Jul 14;65(13):9312-9327. doi: 10.1021/acs.jmedchem.2c00604. Epub 2022 Jun 16. J Med Chem. 2022. PMID: 35709396

8

Discovery, Optimization, and Evaluation of Potent and Selective PI3Kδ-γ Dual Inhibitors for the Treatment of B-cell Malignancies.

Liu K, Zheng W, Chen Y, Tang M, Li D, Deng D, Yang T, Zhang C, Liu J, Yuan X, Shi M, Li X, Guo Y, Zhou Y, Zhao M, Chen L. Liu K, et al. Among authors: liu j. J Med Chem. 2022 Jul 28;65(14):9893-9917. doi: 10.1021/acs.jmedchem.2c00568. Epub 2022 Jul 13. J Med Chem. 2022. PMID: 35831917

9

SKLB-14b, a novel oral microtubule-destabilizing agent based on hydroxamic acid with potent anti-tumor and anti-multidrug resistance activities.

Zhang W, Yang L, Si W, Tang M, Bai P, Zhu Z, Kuang S, Liu J, Shi M, Huang J, Chen X, Li D, Wen Y, Yang Z, Xiao K, Chen L. Zhang W, et al. Among authors: liu j. Bioorg Chem. 2022 Nov;128:106053. doi: 10.1016/j.bioorg.2022.106053. Epub 2022 Aug 1. Bioorg Chem. 2022. PMID: 35964504

10

Correction to "Discovery of a Series of Hydroxamic Acid-Based Microtubule Destabilizing Agents with Potent Antitumor Activity".

Yang L, Zhang W, Qiu Q, Su Z, Tang M, Bai P, Si W, Zhu Z, Liu Y, Yang J, Kuang S, Liu J, Yan W, Shi M, Ye H, Yang Z, Chen L. Yang L, et al. Among authors: liu j, liu y. J Med Chem. 2022 Sep 8;65(17):11890. doi: 10.1021/acs.jmedchem.2c01176. Epub 2022 Aug 23. J Med Chem. 2022. PMID: 35998325 No abstract available.

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