Chen L - Search Results

1

Dasatinib-SIK2 Binding Elucidated by Homology Modeling, Molecular Docking, and Dynamics Simulations.

Shi M, Wang L, Li P, Liu J, Chen L, Xu D. Shi M, et al. Among authors: chen l. ACS Omega. 2021 Apr 15;6(16):11025-11038. doi: 10.1021/acsomega.1c00947. eCollection 2021 Apr 27. ACS Omega. 2021. PMID: 34056256 Free PMC article.

2

Identification, characterization and HPLC quantification of formulation-related impurities of honokiol, an antitumor natural drug candidate in clinical trials.

Wu W, Tang MH, Tang H, Chen K, Fu J, Wang L, Xue LL, Peng A, Ye H, Chen LJ. Wu W, et al. Among authors: chen k, chen lj. J Pharm Biomed Anal. 2018 May 10;153:186-192. doi: 10.1016/j.jpba.2018.02.033. Epub 2018 Feb 21. J Pharm Biomed Anal. 2018. PMID: 29499462

3

Flavonoids from the stems of Millettia pachyloba Drake mediate cytotoxic activity through apoptosis and autophagy in cancer cells.

Yan W, Yang J, Tang H, Xue L, Chen K, Wang L, Zhao M, Tang M, Peng A, Long C, Chen X, Ye H, Chen L. Yan W, et al. Among authors: chen k, chen l, chen x. J Adv Res. 2019 Jun 21;20:117-127. doi: 10.1016/j.jare.2019.06.002. eCollection 2019 Nov. J Adv Res. 2019. PMID: 31338224 Free PMC article.

4

Alkaloids from Black Pepper (Piper nigrum L.) Exhibit Anti-Inflammatory Activity in Murine Macrophages by Inhibiting Activation of NF-κB Pathway.

Pei H, Xue L, Tang M, Tang H, Kuang S, Wang L, Ma X, Cai X, Li Y, Zhao M, Peng A, Ye H, Chen L. Pei H, et al. Among authors: chen l. J Agric Food Chem. 2020 Feb 26;68(8):2406-2417. doi: 10.1021/acs.jafc.9b07754. Epub 2020 Feb 18. J Agric Food Chem. 2020. PMID: 32031370

5

Modulation of LPS-induced inflammation in RAW264.7 murine cells by novel isoflavonoids from Millettia pulchra.

Xue LL, Wu WS, Ma X, Pei HY, Tang MH, Kuang S, Cai XY, Wang L, Li Y, Zhang RJ, Hong F, Peng AH, Ye HY, Chen LJ. Xue LL, et al. Among authors: chen lj. Bioorg Chem. 2020 Apr;97:103693. doi: 10.1016/j.bioorg.2020.103693. Epub 2020 Feb 22. Bioorg Chem. 2020. PMID: 32120079

6

Identification and optimization of piperine analogues as neuroprotective agents for the treatment of Parkinson's disease via the activation of Nrf2/keap1 pathway.

Wang L, Cai X, Shi M, Xue L, Kuang S, Xu R, Qi W, Li Y, Ma X, Zhang R, Hong F, Ye H, Chen L. Wang L, et al. Among authors: chen l. Eur J Med Chem. 2020 Aug 1;199:112385. doi: 10.1016/j.ejmech.2020.112385. Epub 2020 May 5. Eur J Med Chem. 2020. PMID: 32402936

7

Flavonoids with Inhibitory Effects on NLRP3 Inflammasome Activation from Millettia velutina.

Ma X, Zhao M, Tang MH, Xue LL, Zhang RJ, Liu L, Ni HF, Cai XY, Kuang S, Hong F, Wang L, Chen K, Tang H, Li Y, Peng AH, Yang JH, Pei HY, Ye HY, Chen LJ. Ma X, et al. Among authors: chen k, chen lj. J Nat Prod. 2020 Oct 23;83(10):2950-2959. doi: 10.1021/acs.jnatprod.0c00478. Epub 2020 Sep 29. J Nat Prod. 2020. PMID: 32989985

8

Synthesis and evaluation of new compounds bearing 3-(4-aminopiperidin-1-yl)methyl magnolol scaffold as anticancer agents for the treatment of non-small cell lung cancer via targeting autophagy.

Zhao M, Zheng YH, Zhao QY, Zheng W, Yang JH, Pei HY, Liu L, Liu KJ, Xue LL, Deng DX, Wang L, Ma X, Fu SH, Peng AH, Tang MH, Luo YZ, Ye HY, Chen LJ. Zhao M, et al. Among authors: chen lj. Eur J Med Chem. 2021 Jan 1;209:112922. doi: 10.1016/j.ejmech.2020.112922. Epub 2020 Oct 10. Eur J Med Chem. 2021. PMID: 33069436

9

N-(Pyrimidin-2-yl)-1,2,3,4-tetrahydroisoquinolin-6-amine Derivatives as Selective Janus Kinase 2 Inhibitors for the Treatment of Myeloproliferative Neoplasms.

Yang T, Hu M, Chen Y, Xiang M, Tang M, Qi W, Shi M, He J, Yuan X, Zhang C, Liu K, Li J, Yang Z, Chen L. Yang T, et al. Among authors: chen l, chen y. J Med Chem. 2020 Dec 10;63(23):14921-14936. doi: 10.1021/acs.jmedchem.0c01488. Epub 2020 Nov 30. J Med Chem. 2020. PMID: 33256400

10

Design, Synthesis, and Bioactivity Evaluation of Dual-Target Inhibitors of Tubulin and Src Kinase Guided by Crystal Structure.

Wang L, Zheng Y, Li D, Yang J, Lei L, Yan W, Zheng W, Tang M, Shi M, Zhang R, Cai X, Ni H, Ma X, Li N, Hong F, Ye H, Chen L. Wang L, et al. Among authors: chen l. J Med Chem. 2021 Jun 24;64(12):8127-8141. doi: 10.1021/acs.jmedchem.0c01961. Epub 2021 Jun 3. J Med Chem. 2021. PMID: 34081857

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