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PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR.
Ghosh S, Nataraj NB, Noronha A, Patkar S, Sekar A, Mukherjee S, Winograd-Katz S, Kramarski L, Verma A, Lindzen M, Garcia DD, Green J, Eisenberg G, Gil-Henn H, Basu A, Lender Y, Weiss S, Oren M, Lotem M, Geiger B, Ruppin E, Yarden Y. Ghosh S, et al. Among authors: nataraj nb. Cell Rep. 2021 May 25;35(8):109181. doi: 10.1016/j.celrep.2021.109181. Cell Rep. 2021. PMID: 34038737 Free PMC article.
Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression.
Cohen-Dvashi H, Ben-Chetrit N, Russell R, Carvalho S, Lauriola M, Nisani S, Mancini M, Nataraj N, Kedmi M, Roth L, Köstler W, Zeisel A, Yitzhaky A, Zylberg J, Tarcic G, Eilam R, Wigelman Y, Will R, Lavi S, Porat Z, Wiemann S, Ricardo S, Schmitt F, Caldas C, Yarden Y. Cohen-Dvashi H, et al. EMBO Mol Med. 2015 Mar;7(3):299-314. doi: 10.15252/emmm.201404134. EMBO Mol Med. 2015. PMID: 25678558 Free PMC article.
ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma.
Srivastava S, Nataraj NB, Sekar A, Ghosh S, Bornstein C, Drago-Garcia D, Roth L, Romaniello D, Marrocco I, David E, Gilad Y, Lauriola M, Rotkopf R, Kimchi A, Haga Y, Tsutsumi Y, Mirabeau O, Surdez D, Zinovyev A, Delattre O, Kovar H, Amit I, Yarden Y. Srivastava S, et al. Among authors: nataraj nb. Cell Rep. 2019 Oct 1;29(1):104-117.e4. doi: 10.1016/j.celrep.2019.08.088. Cell Rep. 2019. PMID: 31577941 Free PMC article.
Host-Dependent Phenotypic Resistance to EGFR Tyrosine Kinase Inhibitors.
Haga Y, Marrocco I, Noronha A, Uribe ML, Nataraj NB, Sekar A, Drago-Garcia D, Borgoni S, Lindzen M, Giri S, Wiemann S, Tsutsumi Y, Yarden Y. Haga Y, et al. Among authors: nataraj nb. Cancer Res. 2021 Jul 15;81(14):3862-3875. doi: 10.1158/0008-5472.CAN-20-3555. Epub 2021 May 3. Cancer Res. 2021. PMID: 33941614 Free PMC article.
Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53.
Lindzen M, Ghosh S, Noronha A, Drago D, Nataraj NB, Leitner O, Carvalho S, Zmora E, Sapoznik S, Shany KB, Levanon K, Aderka D, Ramírez BS, Dahlhoff M, McNeish I, Yarden Y. Lindzen M, et al. Among authors: nataraj nb. Oncogene. 2021 May;40(21):3665-3679. doi: 10.1038/s41388-021-01784-8. Epub 2021 Apr 30. Oncogene. 2021. PMID: 33941851 Free PMC article.
TP53 missense mutations in PDAC are associated with enhanced fibrosis and an immunosuppressive microenvironment.
Maddalena M, Mallel G, Nataraj NB, Shreberk-Shaked M, Hassin O, Mukherjee S, Arandkar S, Rotkopf R, Kapsack A, Lambiase G, Pellegrino B, Ben-Isaac E, Golani O, Addadi Y, Hajaj E, Eilam R, Straussman R, Yarden Y, Lotem M, Oren M. Maddalena M, et al. Among authors: nataraj nb. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2025631118. doi: 10.1073/pnas.2025631118. Proc Natl Acad Sci U S A. 2021. PMID: 34088837 Free PMC article.
TSHZ2 is an EGF-regulated tumor suppressor that binds to the cytokinesis regulator PRC1 and inhibits metastasis.
Uribe ML, Dahlhoff M, Batra RN, Nataraj NB, Haga Y, Drago-Garcia D, Marrocco I, Sekar A, Ghosh S, Vaknin I, Lebon S, Kramarski L, Tsutsumi Y, Choi I, Rueda OM, Caldas C, Yarden Y. Uribe ML, et al. Among authors: nataraj nb. Sci Signal. 2021 Jun 22;14(688):eabe6156. doi: 10.1126/scisignal.abe6156. Sci Signal. 2021. PMID: 34158398 Free PMC article.
23 results