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Page 1
Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical Efficacy in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease.
Grand DL, Gosling M, Baettig U, Bahra P, Bala K, Brocklehurst C, Budd E, Butler R, Cheung AK, Choudhury H, Collingwood SP, Cox B, Danahay H, Edwards L, Everatt B, Glaenzel U, Glotin AL, Groot-Kormelink P, Hall E, Hatto J, Howsham C, Hughes G, King A, Koehler J, Kulkarni S, Lightfoot M, Nicholls I, Page C, Pergl-Wilson G, Popa MO, Robinson R, Rowlands D, Sharp T, Spendiff M, Stanley E, Steward O, Taylor RJ, Tranter P, Wagner T, Watson H, Williams G, Wright P, Young A, Sandham DA. Grand DL, et al. Among authors: nicholls i. J Med Chem. 2021 Jun 10;64(11):7241-7260. doi: 10.1021/acs.jmedchem.1c00343. Epub 2021 May 24. J Med Chem. 2021. PMID: 34028270
Safety and efficacy of the cystic fibrosis transmembrane conductance regulator potentiator icenticaftor (QBW251).
Kazani S, Rowlands DJ, Bottoli I, Milojevic J, Alcantara J, Jones I, Kulmatycki K, Machineni S, Mostovy L, Nicholls I, Nick JA, Rowe SM, Simmonds NJ, Vegesna R, Verheijen J, Danahay H, Gosling M, Ayalavajjala PS, Salman M, Strieter R. Kazani S, et al. Among authors: nicholls i. J Cyst Fibros. 2021 Mar;20(2):250-256. doi: 10.1016/j.jcf.2020.11.002. Epub 2020 Dec 6. J Cyst Fibros. 2021. PMID: 33293212 Free PMC article.
Synthetic human serum albumin Sudlow I binding site mimics.
Karlsson BC, Rosengren AM, Näslund I, Andersson PO, Nicholls IA. Karlsson BC, et al. Among authors: nicholls ia. J Med Chem. 2010 Nov 25;53(22):7932-7. doi: 10.1021/jm100491v. Epub 2010 Oct 25. J Med Chem. 2010. PMID: 20973485
In situ detection of warfarin using time-correlated single-photon counting.
Rosengren AM, Karlsson BC, Näslund I, Andersson PO, Nicholls IA. Rosengren AM, et al. Among authors: nicholls ia. Biochem Biophys Res Commun. 2011 Apr 1;407(1):60-2. doi: 10.1016/j.bbrc.2011.02.103. Epub 2011 Feb 24. Biochem Biophys Res Commun. 2011. PMID: 21354105
Towards a synthetic avidin mimic.
Wiklander J, Karlsson BC, Aastrup T, Nicholls IA. Wiklander J, et al. Anal Bioanal Chem. 2011 May;400(5):1397-404. doi: 10.1007/s00216-011-4907-5. Epub 2011 Mar 27. Anal Bioanal Chem. 2011. PMID: 21442363
Rational design of biomimetic molecularly imprinted materials: theoretical and computational strategies for guiding nanoscale structured polymer development.
Nicholls IA, Andersson HS, Golker K, Henschel H, Karlsson BC, Olsson GD, Rosengren AM, Shoravi S, Suriyanarayanan S, Wiklander JG, Wikman S. Nicholls IA, et al. Anal Bioanal Chem. 2011 Jun;400(6):1771-86. doi: 10.1007/s00216-011-4935-1. Epub 2011 Apr 9. Anal Bioanal Chem. 2011. PMID: 21475943 Review.
128 results