Nimmerjahn F - Search Results

1

CD137 (4-1BB) stimulation leads to metabolic and functional reprogramming of human monocytes/macrophages enhancing their tumoricidal activity.

Stoll A, Bruns H, Fuchs M, Völkl S, Nimmerjahn F, Kunz M, Peipp M, Mackensen A, Mougiakakos D. Stoll A, et al. Among authors: nimmerjahn f. Leukemia. 2021 Dec;35(12):3482-3496. doi: 10.1038/s41375-021-01287-1. Epub 2021 May 21. Leukemia. 2021. PMID: 34021248 Free PMC article.

2

The novel tribody [(CD20)(2)xCD16] efficiently triggers effector cell-mediated lysis of malignant B cells.

Glorius P, Baerenwaldt A, Kellner C, Staudinger M, Dechant M, Stauch M, Beurskens FJ, Parren PW, Winkel JG, Valerius T, Humpe A, Repp R, Gramatzki M, Nimmerjahn F, Peipp M. Glorius P, et al. Among authors: nimmerjahn f. Leukemia. 2013 Jan;27(1):190-201. doi: 10.1038/leu.2012.150. Epub 2012 Jun 4. Leukemia. 2013. PMID: 22660187

3

A humanized mouse identifies the bone marrow as a niche with low therapeutic IgG activity.

Lux A, Seeling M, Baerenwaldt A, Lehmann B, Schwab I, Repp R, Meidenbauer N, Mackensen A, Hartmann A, Heidkamp G, Dudziak D, Nimmerjahn F. Lux A, et al. Among authors: nimmerjahn f. Cell Rep. 2014 Apr 10;7(1):236-48. doi: 10.1016/j.celrep.2014.02.041. Epub 2014 Mar 27. Cell Rep. 2014. PMID: 24685130 Free article.

4

bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody-mediated immune activation and repression.

Gordan S, Biburger M, Nimmerjahn F. Gordan S, et al. Among authors: nimmerjahn f. Immunol Rev. 2015 Nov;268(1):52-65. doi: 10.1111/imr.12347. Immunol Rev. 2015. PMID: 26497512 Review.

5

Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment.

Heidkamp GF, Sander J, Lehmann CHK, Heger L, Eissing N, Baranska A, Lühr JJ, Hoffmann A, Reimer KC, Lux A, Söder S, Hartmann A, Zenk J, Ulas T, McGovern N, Alexiou C, Spriewald B, Mackensen A, Schuler G, Schauf B, Forster A, Repp R, Fasching PA, Purbojo A, Cesnjevar R, Ullrich E, Ginhoux F, Schlitzer A, Nimmerjahn F, Schultze JL, Dudziak D. Heidkamp GF, et al. Among authors: nimmerjahn f. Sci Immunol. 2016 Dec 16;1(6):eaai7677. doi: 10.1126/sciimmunol.aai7677. Epub 2016 Dec 16. Sci Immunol. 2016. PMID: 28783692

6

Minimal B Cell Extrinsic IgG Glycan Modifications of Pro- and Anti-Inflammatory IgG Preparations in vivo.

Schaffert A, Hanić M, Novokmet M, Zaytseva O, Krištić J, Lux A, Nitschke L, Peipp M, Pezer M, Hennig R, Rapp E, Lauc G, Nimmerjahn F. Schaffert A, et al. Among authors: nimmerjahn f. Front Immunol. 2020 Jan 9;10:3024. doi: 10.3389/fimmu.2019.03024. eCollection 2019. Front Immunol. 2020. PMID: 31998308 Free PMC article.

7

Fc-engineering significantly improves the recruitment of immune effector cells by anti-ICAM-1 antibody MSH-TP15 for myeloma therapy.

Klausz K, Cieker M, Kellner C, Rösner T, Otte A, Krohn S, Lux A, Nimmerjahn F, Valerius T, Gramatzki M, Peipp M. Klausz K, et al. Among authors: nimmerjahn f. Haematologica. 2021 Jul 1;106(7):1857-1866. doi: 10.3324/haematol.2020.251371. Haematologica. 2021. PMID: 32499243 Free PMC article.

8

Complement-Dependent Activity of CD20-Specific IgG Correlates With Bivalent Antigen Binding and C1q Binding Strength.

Bondza S, Marosan A, Kara S, Lösing J, Peipp M, Nimmerjahn F, Buijs J, Lux A. Bondza S, et al. Among authors: nimmerjahn f. Front Immunol. 2021 Jan 11;11:609941. doi: 10.3389/fimmu.2020.609941. eCollection 2020. Front Immunol. 2021. PMID: 33505398 Free PMC article.

9

Select hyperactivating NLRP3 ligands enhance the T_H1- and T_H17-inducing potential of human type 2 conventional dendritic cells.

Hatscher L, Lehmann CHK, Purbojo A, Onderka C, Liang C, Hartmann A, Cesnjevar R, Bruns H, Gross O, Nimmerjahn F, Ivanović-Burmazović I, Kunz M, Heger L, Dudziak D. Hatscher L, et al. Among authors: nimmerjahn f. Sci Signal. 2021 Apr 27;14(680):eabe1757. doi: 10.1126/scisignal.abe1757. Sci Signal. 2021. PMID: 33906973

10

Dual Fc optimization to increase the cytotoxic activity of a CD19-targeting antibody.

Gehlert CL, Rahmati P, Boje AS, Winterberg D, Krohn S, Theocharis T, Cappuzzello E, Lux A, Nimmerjahn F, Ludwig RJ, Lustig M, Rösner T, Valerius T, Schewe DM, Kellner C, Klausz K, Peipp M. Gehlert CL, et al. Among authors: nimmerjahn f. Front Immunol. 2022 Aug 31;13:957874. doi: 10.3389/fimmu.2022.957874. eCollection 2022. Front Immunol. 2022. PMID: 36119088 Free PMC article.

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