Kim HS - Search Results

1

Integrative single-cell analysis of allele-specific copy number alterations and chromatin accessibility in cancer.

Wu CY, Lau BT, Kim HS, Sathe A, Grimes SM, Ji HP, Zhang NR. Wu CY, et al. Among authors: kim hs. Nat Biotechnol. 2021 Oct;39(10):1259-1269. doi: 10.1038/s41587-021-00911-w. Epub 2021 May 20. Nat Biotechnol. 2021. PMID: 34017141 Free PMC article.

2

New approaches to moderate CRISPR-Cas9 activity: Addressing issues of cellular uptake and endosomal escape.

van Hees M, Slott S, Hansen AH, Kim HS, Ji HP, Astakhova K. van Hees M, et al. Among authors: kim hs. Mol Ther. 2022 Jan 5;30(1):32-46. doi: 10.1016/j.ymthe.2021.06.003. Epub 2021 Jun 4. Mol Ther. 2022. PMID: 34091053 Free PMC article. Review.

3

Single-cell characterization of CRISPR-modified transcript isoforms with nanopore sequencing.

Kim HS, Grimes SM, Hooker AC, Lau BT, Ji HP. Kim HS, et al. Genome Biol. 2021 Dec 6;22(1):331. doi: 10.1186/s13059-021-02554-1. Genome Biol. 2021. PMID: 34872615 Free PMC article.

4

Single-cell multi-gene identification of somatic mutations and gene rearrangements in cancer.

Grimes SM, Kim HS, Roy S, Sathe A, Ayala CI, Bai X, Almeda-Notestine AF, Haebe S, Shree T, Levy R, Lau BT, Ji HP. Grimes SM, et al. Among authors: kim hs. NAR Cancer. 2023 Jul 10;5(3):zcad034. doi: 10.1093/narcan/zcad034. eCollection 2023 Sep. NAR Cancer. 2023. PMID: 37435532 Free PMC article.

5

Direct measurement of engineered cancer mutations and their transcriptional phenotypes in single cells.

Kim HS, Grimes SM, Chen T, Sathe A, Lau BT, Hwang GH, Bae S, Ji HP. Kim HS, et al. Nat Biotechnol. 2024 Aug;42(8):1254-1262. doi: 10.1038/s41587-023-01949-8. Epub 2023 Sep 11. Nat Biotechnol. 2024. PMID: 37697151 Free PMC article.

6

Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy.

Ryu SM, Koo T, Kim K, Lim K, Baek G, Kim ST, Kim HS, Kim DE, Lee H, Chung E, Kim JS. Ryu SM, et al. Among authors: kim st, kim de, kim js, kim hs, kim k. Nat Biotechnol. 2018 Jul;36(6):536-539. doi: 10.1038/nbt.4148. Epub 2018 Apr 27. Nat Biotechnol. 2018. PMID: 29702637

7

Adenine base editors catalyze cytosine conversions in human cells.

Kim HS, Jeong YK, Hur JK, Kim JS, Bae S. Kim HS, et al. Among authors: kim js. Nat Biotechnol. 2019 Oct;37(10):1145-1148. doi: 10.1038/s41587-019-0254-4. Epub 2019 Sep 23. Nat Biotechnol. 2019. PMID: 31548727

8

Microhomology-based choice of Cas9 nuclease target sites.

Bae S, Kweon J, Kim HS, Kim JS. Bae S, et al. Among authors: kim js, kim hs. Nat Methods. 2014 Jul;11(7):705-6. doi: 10.1038/nmeth.3015. Nat Methods. 2014. PMID: 24972169 No abstract available.

9

CRISPR-sub: Analysis of DNA substitution mutations caused by CRISPR-Cas9 in human cells.

Hwang GH, Yu J, Yang S, Son WJ, Lim K, Kim HS, Kim JS, Bae S. Hwang GH, et al. Among authors: kim js, kim hs. Comput Struct Biotechnol J. 2020 Jun 25;18:1686-1694. doi: 10.1016/j.csbj.2020.06.026. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 32670508 Free PMC article.

10

Large DNA deletions occur during DNA repair at 20-fold lower frequency for base editors and prime editors than for Cas9 nucleases.

Hwang GH, Lee SH, Oh M, Kim S, Habib O, Jang HK, Kim HS, Kim Y, Kim CH, Kim S, Bae S. Hwang GH, et al. Among authors: kim ch, kim s, kim hs, kim y. Nat Biomed Eng. 2024 Nov 4. doi: 10.1038/s41551-024-01277-5. Online ahead of print. Nat Biomed Eng. 2024. PMID: 39496933

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