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Structural insights on ligand recognition at the human leukotriene B4 receptor 1.
Michaelian N, Sadybekov A, Besserer-Offroy É, Han GW, Krishnamurthy H, Zamlynny BA, Fradera X, Siliphaivanh P, Presland J, Spencer KB, Soisson SM, Popov P, Sarret P, Katritch V, Cherezov V. Michaelian N, et al. Among authors: popov p. Nat Commun. 2021 May 20;12(1):2971. doi: 10.1038/s41467-021-23149-1. Nat Commun. 2021. PMID: 34016973 Free PMC article.
Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.
Batyuk A, Galli L, Ishchenko A, Han GW, Gati C, Popov PA, Lee MY, Stauch B, White TA, Barty A, Aquila A, Hunter MS, Liang M, Boutet S, Pu M, Liu ZJ, Nelson G, James D, Li C, Zhao Y, Spence JC, Liu W, Fromme P, Katritch V, Weierstall U, Stevens RC, Cherezov V. Batyuk A, et al. Among authors: popov pa. Sci Adv. 2016 Sep 23;2(9):e1600292. doi: 10.1126/sciadv.1600292. eCollection 2016 Sep. Sci Adv. 2016. PMID: 27679816 Free PMC article.
5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.
Peng Y, McCorvy JD, Harpsøe K, Lansu K, Yuan S, Popov P, Qu L, Pu M, Che T, Nikolajsen LF, Huang XP, Wu Y, Shen L, Bjørn-Yoshimoto WE, Ding K, Wacker D, Han GW, Cheng J, Katritch V, Jensen AA, Hanson MA, Zhao S, Gloriam DE, Roth BL, Stevens RC, Liu ZJ. Peng Y, et al. Among authors: popov p. Cell. 2018 Feb 8;172(4):719-730.e14. doi: 10.1016/j.cell.2018.01.001. Epub 2018 Feb 1. Cell. 2018. PMID: 29398112 Free PMC article.
Crystal structure of the Frizzled 4 receptor in a ligand-free state.
Yang S, Wu Y, Xu TH, de Waal PW, He Y, Pu M, Chen Y, DeBruine ZJ, Zhang B, Zaidi SA, Popov P, Guo Y, Han GW, Lu Y, Suino-Powell K, Dong S, Harikumar KG, Miller LJ, Katritch V, Xu HE, Shui W, Stevens RC, Melcher K, Zhao S, Xu F. Yang S, et al. Among authors: popov p. Nature. 2018 Aug;560(7720):666-670. doi: 10.1038/s41586-018-0447-x. Epub 2018 Aug 22. Nature. 2018. PMID: 30135577
Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor.
Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, Katritch V, Cherezov V, Hanson MA, Stevens RC. Audet M, et al. Among authors: popov p. Nat Chem Biol. 2019 Jan;15(1):11-17. doi: 10.1038/s41589-018-0160-y. Epub 2018 Dec 3. Nat Chem Biol. 2019. PMID: 30510194 Free PMC article.
Crystal Structure of the Human Cannabinoid Receptor CB2.
Li X, Hua T, Vemuri K, Ho JH, Wu Y, Wu L, Popov P, Benchama O, Zvonok N, Locke K, Qu L, Han GW, Iyer MR, Cinar R, Coffey NJ, Wang J, Wu M, Katritch V, Zhao S, Kunos G, Bohn LM, Makriyannis A, Stevens RC, Liu ZJ. Li X, et al. Among authors: popov p. Cell. 2019 Jan 24;176(3):459-467.e13. doi: 10.1016/j.cell.2018.12.011. Epub 2019 Jan 10. Cell. 2019. PMID: 30639103 Free PMC article.
Computational design for thermostabilization of GPCRs.
Popov P, Kozlovskii I, Katritch V. Popov P, et al. Curr Opin Struct Biol. 2019 Apr;55:25-33. doi: 10.1016/j.sbi.2019.02.010. Epub 2019 Mar 23. Curr Opin Struct Biol. 2019. PMID: 30909106 Review.
Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
Luginina A, Gusach A, Marin E, Mishin A, Brouillette R, Popov P, Shiriaeva A, Besserer-Offroy É, Longpré JM, Lyapina E, Ishchenko A, Patel N, Polovinkin V, Safronova N, Bogorodskiy A, Edelweiss E, Hu H, Weierstall U, Liu W, Batyuk A, Gordeliy V, Han GW, Sarret P, Katritch V, Borshchevskiy V, Cherezov V. Luginina A, et al. Among authors: popov p. Sci Adv. 2019 Oct 9;5(10):eaax2518. doi: 10.1126/sciadv.aax2518. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31633023 Free PMC article.
265 results