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Page 1
Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate.
Prieto-Fernández E, Egia-Mendikute L, Vila-Vecilla L, Bosch A, Barreira-Manrique A, Lee SY, García-Del Río A, Antoñana-Vildosola A, Jiménez-Lasheras B, Moreno-Cugnon L, Jiménez-Barbero J, Berra E, Ereño-Orbea J, Palazon A. Prieto-Fernández E, et al. Among authors: moreno cugnon l. Emerg Microbes Infect. 2021 Dec;10(1):1065-1076. doi: 10.1080/22221751.2021.1932607. Emerg Microbes Infect. 2021. PMID: 34013835 Free PMC article.
HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis.
Palomo-Irigoyen M, Pérez-Andrés E, Iruarrizaga-Lejarreta M, Barreira-Manrique A, Tamayo-Caro M, Vila-Vecilla L, Moreno-Cugnon L, Beitia N, Medrano D, Fernández-Ramos D, Lozano JJ, Okawa S, Lavín JL, Martín-Martín N, Sutherland JD, de Juan VG, Gonzalez-Lopez M, Macías-Cámara N, Mosén-Ansorena D, Laraba L, Hanemann CO, Ercolano E, Parkinson DB, Schultz CW, Araúzo-Bravo MJ, Ascensión AM, Gerovska D, Iribar H, Izeta A, Pytel P, Krastel P, Provenzani A, Seneci P, Carrasco RD, Del Sol A, Martinez-Chantar ML, Barrio R, Serra E, Lazaro C, Flanagan AM, Gorospe M, Ratner N, Aransay AM, Carracedo A, Varela-Rey M, Woodhoo A. Palomo-Irigoyen M, et al. Among authors: moreno cugnon l. J Clin Invest. 2020 Jul 1;130(7):3848-3864. doi: 10.1172/JCI130379. J Clin Invest. 2020. PMID: 32315290 Free PMC article.
Elevated p38MAPK activity promotes neural stem cell aging.
Moreno-Cugnon L, Arrizabalaga O, Llarena I, Matheu A. Moreno-Cugnon L, et al. Aging (Albany NY). 2020 Apr 3;12(7):6030-6036. doi: 10.18632/aging.102994. Epub 2020 Apr 3. Aging (Albany NY). 2020. PMID: 32243258 Free PMC article.
SOX2 haploinsufficiency promotes impaired vision at advanced age.
Moreno-Cugnon L, Anasagasti A, Ezquerra-Inchausti M, Izeta A, de la Villa P, Ruiz-Ederra J, Matheu A. Moreno-Cugnon L, et al. Oncotarget. 2018 Nov 30;9(94):36684-36692. doi: 10.18632/oncotarget.26393. eCollection 2018 Nov 30. Oncotarget. 2018. PMID: 30613351 Free PMC article.
SOX2 expression diminishes with ageing in several tissues in mice and humans.
Carrasco-Garcia E, Moreno-Cugnon L, Garcia I, Borras C, Revuelta M, Izeta A, Lopez-Lluch G, de Pancorbo MM, Vergara I, Vina J, Matheu A. Carrasco-Garcia E, et al. Mech Ageing Dev. 2019 Jan;177:30-36. doi: 10.1016/j.mad.2018.03.008. Epub 2018 Mar 21. Mech Ageing Dev. 2019. PMID: 29574045
Increased Arf/p53 activity in stem cells, aging and cancer.
Carrasco-Garcia E, Moreno M, Moreno-Cugnon L, Matheu A. Carrasco-Garcia E, et al. Aging Cell. 2017 Apr;16(2):219-225. doi: 10.1111/acel.12574. Epub 2017 Jan 19. Aging Cell. 2017. PMID: 28101907 Free PMC article. Review.
mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.
Garros-Regulez L, Aldaz P, Arrizabalaga O, Moncho-Amor V, Carrasco-Garcia E, Manterola L, Moreno-Cugnon L, Barrena C, Villanua J, Ruiz I, Pollard S, Lovell-Badge R, Sampron N, Garcia I, Matheu A. Garros-Regulez L, et al. Expert Opin Ther Targets. 2016;20(4):393-405. doi: 10.1517/14728222.2016.1151002. Expert Opin Ther Targets. 2016. PMID: 26878385 Free PMC article.
Oncogenic activity of SOX1 in glioblastoma.
Garcia I, Aldaregia J, Marjanovic Vicentic J, Aldaz P, Moreno-Cugnon L, Torres-Bayona S, Carrasco-Garcia E, Garros-Regulez L, Egaña L, Rubio A, Pollard S, Stevanovic M, Sampron N, Matheu A. Garcia I, et al. Sci Rep. 2017 Apr 20;7:46575. doi: 10.1038/srep46575. Sci Rep. 2017. PMID: 28425506 Free PMC article.
High expression of MKP1/DUSP1 counteracts glioma stem cell activity and mediates HDAC inhibitor response.
Arrizabalaga O, Moreno-Cugnon L, Auzmendi-Iriarte J, Aldaz P, Ibanez de Caceres I, Garros-Regulez L, Moncho-Amor V, Torres-Bayona S, Pernía O, Pintado-Berninches L, Carrasco-Ramirez P, Cortes-Sempere M, Rosas R, Sanchez-Gomez P, Ruiz I, Caren H, Pollard S, Garcia I, Sacido AA, Lovell-Badge R, Belda-Iniesta C, Sampron N, Perona R, Matheu A. Arrizabalaga O, et al. Oncogenesis. 2017 Dec 14;6(12):401. doi: 10.1038/s41389-017-0003-9. Oncogenesis. 2017. PMID: 29284798 Free PMC article.
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