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Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations.
Jafari N, Del Rio J, Akimoto M, Byun JA, Boulton S, Moleschi K, Alsayyed Y, Swanson P, Huang J, Martinez Pomier K, Lee C, Wu J, Taylor SS, Melacini G. Jafari N, et al. Among authors: melacini g. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2024716118. doi: 10.1073/pnas.2024716118. Proc Natl Acad Sci U S A. 2021. PMID: 34006641 Free PMC article.
cAMP activation of PKA defines an ancient signaling mechanism.
Das R, Esposito V, Abu-Abed M, Anand GS, Taylor SS, Melacini G. Das R, et al. Among authors: melacini g. Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):93-8. doi: 10.1073/pnas.0609033103. Epub 2006 Dec 20. Proc Natl Acad Sci U S A. 2007. PMID: 17182741 Free PMC article.
Mapping allostery through the covariance analysis of NMR chemical shifts.
Selvaratnam R, Chowdhury S, VanSchouwen B, Melacini G. Selvaratnam R, et al. Among authors: melacini g. Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6133-8. doi: 10.1073/pnas.1017311108. Epub 2011 Mar 28. Proc Natl Acad Sci U S A. 2011. PMID: 21444788 Free PMC article.
cAMP-dependent allostery and dynamics in Epac: an NMR view.
Selvaratnam R, Akimoto M, VanSchouwen B, Melacini G. Selvaratnam R, et al. Among authors: melacini g. Biochem Soc Trans. 2012 Feb;40(1):219-23. doi: 10.1042/BST20110628. Biochem Soc Trans. 2012. PMID: 22260694 Review.
Signaling through dynamic linkers as revealed by PKA.
Akimoto M, Selvaratnam R, McNicholl ET, Verma G, Taylor SS, Melacini G. Akimoto M, et al. Among authors: melacini g. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14231-6. doi: 10.1073/pnas.1312644110. Epub 2013 Aug 14. Proc Natl Acad Sci U S A. 2013. PMID: 23946424 Free PMC article.
125 results