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Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations.
Jafari N, Del Rio J, Akimoto M, Byun JA, Boulton S, Moleschi K, Alsayyed Y, Swanson P, Huang J, Martinez Pomier K, Lee C, Wu J, Taylor SS, Melacini G. Jafari N, et al. Among authors: huang j. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2024716118. doi: 10.1073/pnas.2024716118. Proc Natl Acad Sci U S A. 2021. PMID: 34006641 Free PMC article.
Atomic resolution map of the soluble amyloid beta assembly toxic surfaces.
Ahmed R, Akcan M, Khondker A, Rheinstädter MC, Bozelli JC Jr, Epand RM, Huynh V, Wylie RG, Boulton S, Huang J, Verschoor CP, Melacini G. Ahmed R, et al. Among authors: huang j. Chem Sci. 2019 May 21;10(24):6072-6082. doi: 10.1039/c9sc01331h. eCollection 2019 Jun 28. Chem Sci. 2019. PMID: 31360412 Free PMC article.
Mechanism of Action of an EPAC1-Selective Competitive Partial Agonist.
Shao H, Mohamed H, Boulton S, Huang J, Wang P, Chen H, Zhou J, Luchowska-Stańska U, Jentsch NG, Armstrong AL, Magolan J, Yarwood S, Melacini G. Shao H, et al. Among authors: huang j. J Med Chem. 2020 May 14;63(9):4762-4775. doi: 10.1021/acs.jmedchem.9b02151. Epub 2020 Apr 16. J Med Chem. 2020. PMID: 32297742
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