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Thiazolidinedione "Magic Bullets" Simultaneously Targeting PPARγ and HDACs: Design, Synthesis, and Investigations of their In Vitro and In Vivo Antitumor Effects.
Tilekar K, Hess JD, Upadhyay N, Bianco AL, Schweipert M, Laghezza A, Loiodice F, Meyer-Almes FJ, Aguilera RJ, Lavecchia A, C S R. Tilekar K, et al. Among authors: aguilera rj. J Med Chem. 2021 May 27;64(10):6949-6971. doi: 10.1021/acs.jmedchem.1c00491. Epub 2021 May 18. J Med Chem. 2021. PMID: 34006099 Free PMC article.
Novel 3,5-bis(arylidene)-4-oxo-1-piperidinyl dimers: structure-activity relationships and potent antileukemic and antilymphoma cytotoxicity.
Santiago-Vazquez Y, Das S, Das U, Robles-Escajeda E, Ortega NM, Lema C, Varela-Ramírez A, Aguilera RJ, Balzarini J, De Clercq E, Dimmock SG, Gorecki DK, Dimmock JR. Santiago-Vazquez Y, et al. Among authors: aguilera rj. Eur J Med Chem. 2014 Apr 22;77:315-22. doi: 10.1016/j.ejmech.2014.03.009. Epub 2014 Mar 6. Eur J Med Chem. 2014. PMID: 24657568 Free PMC article.
Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential.
Tilekar K, Upadhyay N, Hess JD, Macias LH, Mrowka P, Aguilera RJ, Meyer-Almes FJ, Iancu CV, Choe JY, Ramaa CS. Tilekar K, et al. Among authors: aguilera rj. Eur J Med Chem. 2020 Sep 15;202:112603. doi: 10.1016/j.ejmech.2020.112603. Epub 2020 Jul 2. Eur J Med Chem. 2020. PMID: 32634629 Free PMC article.
Identification of a Potent Cytotoxic Pyrazole with Anti-Breast Cancer Activity That Alters Multiple Pathways.
Gutierrez DA, Contreras L, Villanueva PJ, Borrego EA, Morán-Santibañez K, Hess JD, DeJesus R, Larragoity M, Betancourt AP, Mohl JE, Robles-Escajeda E, Begum K, Roy S, Kirken RA, Varela-Ramirez A, Aguilera RJ. Gutierrez DA, et al. Among authors: aguilera rj. Cells. 2022 Jan 12;11(2):254. doi: 10.3390/cells11020254. Cells. 2022. PMID: 35053370 Free PMC article.
97 results