Lobb I - Search Results

1

SynLeGG: analysis and visualization of multiomics data for discovery of cancer 'Achilles Heels' and gene function relationships.

Wappett M, Harris A, Lubbock ALR, Lobb I, McDade S, Overton IM. Wappett M, et al. Among authors: lobb i. Nucleic Acids Res. 2021 Jul 2;49(W1):W613-W618. doi: 10.1093/nar/gkab338. Nucleic Acids Res. 2021. PMID: 33997893 Free PMC article.

2

Identification of a novel TIF-IA-NF-κB nucleolar stress response pathway.

Chen J, Lobb IT, Morin P, Novo SM, Simpson J, Kennerknecht K, von Kriegsheim A, Batchelor EE, Oakley F, Stark LA. Chen J, et al. Among authors: lobb it. Nucleic Acids Res. 2018 Jul 6;46(12):6188-6205. doi: 10.1093/nar/gky455. Nucleic Acids Res. 2018. PMID: 29873780 Free PMC article.

3

A Role for the Autophagic Receptor, SQSTM1/p62, in Trafficking NF-κB/RelA to Nucleolar Aggresomes.

Lobb IT, Morin P, Martin K, Thoms HC, Wills JC, Lleshi X, Olsen KCF, Duncan RR, Stark LA. Lobb IT, et al. Mol Cancer Res. 2021 Feb;19(2):274-287. doi: 10.1158/1541-7786.MCR-20-0336. Epub 2020 Oct 23. Mol Cancer Res. 2021. PMID: 33097627 Free article.

4

USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF.

Jurisic A, Sung PJ, Wappett M, Daubriac J, Lobb IT, Kung WW, Crawford N, Page N, Cassidy E, Feutren-Burton S, Rountree JSS, Helm MD, O'Dowd CR, Kennedy RD, Gavory G, Cranston AN, Longley DB, Jacq X, Harrison T. Jurisic A, et al. Among authors: lobb it. Clin Transl Med. 2024 Apr;14(4):e1648. doi: 10.1002/ctm2.1648. Clin Transl Med. 2024. PMID: 38602256 Free PMC article.

5

Oxidation modulates LINGO2-induced inactivation of large conductance, Ca²⁺-activated potassium channels.

Dudem S, Boon PX, Mullins N, McClafferty H, Shipston MJ, Wilkinson RDA, Lobb I, Sergeant GP, Thornbury KD, Tikhonova IG, Hollywood MA. Dudem S, et al. Among authors: lobb i. J Biol Chem. 2023 Mar;299(3):102975. doi: 10.1016/j.jbc.2023.102975. Epub 2023 Feb 2. J Biol Chem. 2023. PMID: 36738787 Free PMC article.

6

The HIF complex recruits the histone methyltransferase SET1B to activate specific hypoxia-inducible genes.

Ortmann BM, Burrows N, Lobb IT, Arnaiz E, Wit N, Bailey PSJ, Jordon LH, Lombardi O, Peñalver A, McCaffrey J, Seear R, Mole DR, Ratcliffe PJ, Maxwell PH, Nathan JA. Ortmann BM, et al. Among authors: lobb it. Nat Genet. 2021 Jul;53(7):1022-1035. doi: 10.1038/s41588-021-00887-y. Epub 2021 Jun 21. Nat Genet. 2021. PMID: 34155378 Free PMC article.

7

Endogenous H₂S production deficiencies lead to impaired renal erythropoietin production.

Leigh J, Juriasingani S, Akbari M, Shao P, Saha MN, Lobb I, Bachtler M, Fernandez B, Qian Z, van Goor H, Pasch A, Feelisch M, Wang R, Sener A. Leigh J, et al. Among authors: lobb i. Can Urol Assoc J. 2019 Jul;13(7):E210-E219. doi: 10.5489/cuaj.5658. Can Urol Assoc J. 2019. PMID: 30472982 Free PMC article.

8

Daily therapy with a slow-releasing H₂S donor GYY4137 enables early functional recovery and ameliorates renal injury associated with urinary obstruction.

Lin S, Lian D, Liu W, Haig A, Lobb I, Hijazi A, Razvi H, Burton J, Whiteman M, Sener A. Lin S, et al. Among authors: lobb i. Nitric Oxide. 2018 Jun 1;76:16-28. doi: 10.1016/j.niox.2018.03.002. Epub 2018 Mar 6. Nitric Oxide. 2018. PMID: 29522906

9

MARCH6 and TRC8 facilitate the quality control of cytosolic and tail-anchored proteins.

Stefanovic-Barrett S, Dickson AS, Burr SP, Williamson JC, Lobb IT, van den Boomen DJ, Lehner PJ, Nathan JA. Stefanovic-Barrett S, et al. Among authors: lobb it. EMBO Rep. 2018 May;19(5):e45603. doi: 10.15252/embr.201745603. Epub 2018 Mar 8. EMBO Rep. 2018. PMID: 29519897 Free PMC article.

10

A novel approach to off-clamp partial nephrectomy demonstrates significant improvements in renal injury in an experimental porcine model.

Olvera-Posada D, Lin S, Aboalsamh G, Haig A, Lobb I, Grewal J, Saha MN, Sener A. Olvera-Posada D, et al. Among authors: lobb i. Can Urol Assoc J. 2017 Oct;11(10):E390-E395. doi: 10.5489/cuaj.4305. Can Urol Assoc J. 2017. PMID: 29384471 Free PMC article.

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