Vázquez-Laslop N - Search Results

1

Context-specific action of macrolide antibiotics on the eukaryotic ribosome.

Svetlov MS, Koller TO, Meydan S, Shankar V, Klepacki D, Polacek N, Guydosh NR, Vázquez-Laslop N, Wilson DN, Mankin AS. Svetlov MS, et al. Nat Commun. 2021 May 14;12(1):2803. doi: 10.1038/s41467-021-23068-1. Nat Commun. 2021. PMID: 33990576 Free PMC article.

2

Molecular mechanism of drug-dependent ribosome stalling.

Vazquez-Laslop N, Thum C, Mankin AS. Vazquez-Laslop N, et al. Mol Cell. 2008 Apr 25;30(2):190-202. doi: 10.1016/j.molcel.2008.02.026. Mol Cell. 2008. PMID: 18439898 Free article.

3

Programmed drug-dependent ribosome stalling.

Ramu H, Mankin A, Vazquez-Laslop N. Ramu H, et al. Mol Microbiol. 2009 Feb;71(4):811-24. doi: 10.1111/j.1365-2958.2008.06576.x. Epub 2008 Nov 30. Mol Microbiol. 2009. PMID: 19170872 Free article. Review.

4

The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide.

Vázquez-Laslop N, Ramu H, Klepacki D, Kannan K, Mankin AS. Vázquez-Laslop N, et al. EMBO J. 2010 Sep 15;29(18):3108-17. doi: 10.1038/emboj.2010.180. Epub 2010 Jul 30. EMBO J. 2010. PMID: 20676057 Free PMC article.

5

Nascent peptide in the ribosome exit tunnel affects functional properties of the A-site of the peptidyl transferase center.

Ramu H, Vázquez-Laslop N, Klepacki D, Dai Q, Piccirilli J, Micura R, Mankin AS. Ramu H, et al. Mol Cell. 2011 Feb 4;41(3):321-30. doi: 10.1016/j.molcel.2010.12.031. Mol Cell. 2011. PMID: 21292164 Free article.

6

Picky nascent peptides do not talk to foreign ribosomes.

Vázquez-Laslop N, Mankin AS. Vázquez-Laslop N, et al. Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):5931-2. doi: 10.1073/pnas.1103011108. Epub 2011 Apr 4. Proc Natl Acad Sci U S A. 2011. PMID: 21464303 Free PMC article. No abstract available.

7

Role of antibiotic ligand in nascent peptide-dependent ribosome stalling.

Vázquez-Laslop N, Klepacki D, Mulhearn DC, Ramu H, Krasnykh O, Franzblau S, Mankin AS. Vázquez-Laslop N, et al. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10496-501. doi: 10.1073/pnas.1103474108. Epub 2011 Jun 13. Proc Natl Acad Sci U S A. 2011. PMID: 21670252 Free PMC article.

8

Selective protein synthesis by ribosomes with a drug-obstructed exit tunnel.

Kannan K, Vázquez-Laslop N, Mankin AS. Kannan K, et al. Cell. 2012 Oct 26;151(3):508-20. doi: 10.1016/j.cell.2012.09.018. Cell. 2012. PMID: 23101624 Free article.

9

Deregulation of translation due to post-transcriptional modification of rRNA explains why erm genes are inducible.

Gupta P, Sothiselvam S, Vázquez-Laslop N, Mankin AS. Gupta P, et al. Nat Commun. 2013;4:1984. doi: 10.1038/ncomms2984. Nat Commun. 2013. PMID: 23749080 Free article.

10

Identifying the targets of aminoacyl-tRNA synthetase inhibitors by primer extension inhibition.

Orelle C, Szal T, Klepacki D, Shaw KJ, Vázquez-Laslop N, Mankin AS. Orelle C, et al. Nucleic Acids Res. 2013 Aug;41(14):e144. doi: 10.1093/nar/gkt526. Epub 2013 Jun 12. Nucleic Acids Res. 2013. PMID: 23761439 Free PMC article.

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