Hughes WE - Search Results

1

A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma.

Gonzalez Rajal A, Marzec KA, McCloy RA, Nobis M, Chin V, Hastings JF, Lai K, Kennerson M, Hughes WE, Vaghjiani V, Timpson P, Cain JE, Watkins DN, Croucher DR, Burgess A. Gonzalez Rajal A, et al. Among authors: hughes we. Elife. 2021 May 13;10:e65234. doi: 10.7554/eLife.65234. Elife. 2021. PMID: 33983115 Free PMC article.

2

Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment.

Herrmann D, Conway JR, Vennin C, Magenau A, Hughes WE, Morton JP, Timpson P. Herrmann D, et al. Among authors: hughes we. Carcinogenesis. 2014 Aug;35(8):1671-9. doi: 10.1093/carcin/bgu108. Epub 2014 Jun 5. Carcinogenesis. 2014. PMID: 24903340 Review.

3

Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions.

Jose J, Hoque M, Engel J, Beevi SS, Wahba M, Georgieva MI, Murphy KJ, Hughes WE, Cochran BJ, Lu A, Tebar F, Hoy AJ, Timpson P, Rye KA, Enrich C, Rentero C, Grewal T. Jose J, et al. Among authors: hughes we. Sci Rep. 2022 Jan 12;12(1):596. doi: 10.1038/s41598-021-04584-y. Sci Rep. 2022. PMID: 35022465 Free PMC article.

4

I-motif DNA structures are formed in the nuclei of human cells.

Zeraati M, Langley DB, Schofield P, Moye AL, Rouet R, Hughes WE, Bryan TM, Dinger ME, Christ D. Zeraati M, et al. Among authors: hughes we. Nat Chem. 2018 Jun;10(6):631-637. doi: 10.1038/s41557-018-0046-3. Epub 2018 Apr 23. Nat Chem. 2018. PMID: 29686376

5

Transcriptome profiles of stem-like cells from primary breast cancers allow identification of ITGA7 as a predictive marker of chemotherapy response.

Gwili N, Jones SJ, Amri WA, Carr IM, Harris S, Hogan BV, Hughes WE, Kim B, Langlands FE, Millican-Slater RA, Pramanik A, Thorne JL, Verghese ET, Wells G, Hamza M, Younis L, El Deeb NMF, Hughes TA. Gwili N, et al. Among authors: hughes ta, hughes we. Br J Cancer. 2021 Sep;125(7):983-993. doi: 10.1038/s41416-021-01484-w. Epub 2021 Jul 12. Br J Cancer. 2021. PMID: 34253873 Free PMC article.

6

Identification of RhoGAP22 as an Akt-dependent regulator of cell motility in response to insulin.

Rowland AF, Larance M, Hughes WE, James DE. Rowland AF, et al. Among authors: hughes we. Mol Cell Biol. 2011 Dec;31(23):4789-800. doi: 10.1128/MCB.05583-11. Epub 2011 Oct 3. Mol Cell Biol. 2011. PMID: 21969604 Free PMC article.

7

Annexin A6 stimulates the membrane recruitment of p120GAP to modulate Ras and Raf-1 activity.

Grewal T, Evans R, Rentero C, Tebar F, Cubells L, de Diego I, Kirchhoff MF, Hughes WE, Heeren J, Rye KA, Rinninger F, Daly RJ, Pol A, Enrich C. Grewal T, et al. Among authors: hughes we. Oncogene. 2005 Sep 1;24(38):5809-20. doi: 10.1038/sj.onc.1208743. Oncogene. 2005. PMID: 15940262

8

Inhibition of H-Ras and MAPK is compensated by PKC-dependent pathways in annexin A6 expressing cells.

Rentero C, Evans R, Wood P, Tebar F, Vilà de Muga S, Cubells L, de Diego I, Hayes TE, Hughes WE, Pol A, Rye KA, Enrich C, Grewal T. Rentero C, et al. Among authors: hughes we. Cell Signal. 2006 Jul;18(7):1006-16. doi: 10.1016/j.cellsig.2005.08.008. Epub 2005 Sep 23. Cell Signal. 2006. PMID: 16183252

9

Annexin A6 is a scaffold for PKCα to promote EGFR inactivation.

Koese M, Rentero C, Kota BP, Hoque M, Cairns R, Wood P, Vilà de Muga S, Reverter M, Alvarez-Guaita A, Monastyrskaya K, Hughes WE, Swarbrick A, Tebar F, Daly RJ, Enrich C, Grewal T. Koese M, et al. Among authors: hughes we. Oncogene. 2013 Jun 6;32(23):2858-72. doi: 10.1038/onc.2012.303. Epub 2012 Jul 16. Oncogene. 2013. PMID: 22797061

10

Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic beta-cells from lipoapoptosis.

Busch AK, Gurisik E, Cordery DV, Sudlow M, Denyer GS, Laybutt DR, Hughes WE, Biden TJ. Busch AK, et al. Among authors: hughes we. Diabetes. 2005 Oct;54(10):2917-24. doi: 10.2337/diabetes.54.10.2917. Diabetes. 2005. PMID: 16186393

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