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SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System.
Neyrinck K, Van Den Daele J, Vervliet T, De Smedt J, Wierda K, Nijs M, Vanbokhoven T, D'hondt A, Planque M, Fendt SM, Shih PY, Seibt F, Almenar JP, Kreir M, Kumar D, Broccoli V, Bultynck G, Ebneth A, Cabrera-Socorro A, Verfaillie C. Neyrinck K, et al. Among authors: ebneth a. Stem Cell Rev Rep. 2021 Oct;17(5):1855-1873. doi: 10.1007/s12015-021-10179-x. Epub 2021 May 12. Stem Cell Rev Rep. 2021. PMID: 33982246 Free PMC article.
Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies.
Shih PY, Kreir M, Kumar D, Seibt F, Pestana F, Schmid B, Holst B, Clausen C, Steeg R, Fischer B, Pita-Almenar J, Ebneth A, Cabrera-Socorro A. Shih PY, et al. Among authors: ebneth a. Stem Cell Res. 2021 Jul;54:102386. doi: 10.1016/j.scr.2021.102386. Epub 2021 May 24. Stem Cell Res. 2021. PMID: 34229210 Free article.
Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration.
García-León JA, Cabrera-Socorro A, Eggermont K, Swijsen A, Terryn J, Fazal R, Nami F, Ordovás L, Quiles A, Lluis F, Serneels L, Wierda K, Sierksma A, Kreir M, Pestana F, Van Damme P, De Strooper B, Thorrez L, Ebneth A, Verfaillie CM. García-León JA, et al. Among authors: ebneth a. Alzheimers Dement. 2018 Oct;14(10):1261-1280. doi: 10.1016/j.jalz.2018.05.007. Epub 2018 Jul 20. Alzheimers Dement. 2018. PMID: 30036493 Free article.
Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line.
Schmid B, Prehn KR, Nimsanor N, Garcia BIA, Poulsen U, Jørring I, Rasmussen MA, Clausen C, Mau-Holzmann UA, Ramakrishna S, Muddashetty R, Steeg R, Bruce K, Mackintosh P, Ebneth A, Holst B, Cabrera-Socorro A. Schmid B, et al. Among authors: ebneth a. Stem Cell Res. 2019 Jan;34:101349. doi: 10.1016/j.scr.2018.11.010. Epub 2019 Jan 4. Stem Cell Res. 2019. PMID: 30660866 Free article.
Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (Ɛ2/Ɛ3/Ɛ4) and knock-out for the study of APOE biology in health and disease.
Schmid B, Holst B, Clausen C, Bahnassawy L, Reinhardt P, Bakker MHM, Díaz-Guerra E, Vicario C, Martino-Adami PV, Thoenes M, Ramirez A, Fliessbach K, Grezella C, Brüstle O, Peitz M, Ebneth A, Cabrera-Socorro A. Schmid B, et al. Among authors: ebneth a. Stem Cell Res. 2021 Apr;52:102180. doi: 10.1016/j.scr.2021.102180. Epub 2021 Feb 2. Stem Cell Res. 2021. PMID: 33556820 Free article.
Scalable expansion of iPSC and their derivatives across multiple lineages.
Kwok CK, Sébastien I, Hariharan K, Meiser I, Wihan J, Altmaier S, Karnatz I, Bauer D, Fischer B, Feile A, Cabrera-Socorro A, Rasmussen M, Holst B, Neubauer JC, Clausen C, Verfaillie C, Ebneth A, Hansson M, Steeg R, Zimmermann H. Kwok CK, et al. Among authors: ebneth a. Reprod Toxicol. 2022 Sep;112:23-35. doi: 10.1016/j.reprotox.2022.05.007. Epub 2022 May 17. Reprod Toxicol. 2022. PMID: 35595152 Free article.
Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience.
De Sousa PA, Steeg R, Wachter E, Bruce K, King J, Hoeve M, Khadun S, McConnachie G, Holder J, Kurtz A, Seltmann S, Dewender J, Reimann S, Stacey G, O'Shea O, Chapman C, Healy L, Zimmermann H, Bolton B, Rawat T, Atkin I, Veiga A, Kuebler B, Serano BM, Saric T, Hescheler J, Brüstle O, Peitz M, Thiele C, Geijsen N, Holst B, Clausen C, Lako M, Armstrong L, Gupta SK, Kvist AJ, Hicks R, Jonebring A, Brolén G, Ebneth A, Cabrera-Socorro A, Foerch P, Geraerts M, Stummann TC, Harmon S, George C, Streeter I, Clarke L, Parkinson H, Harrison PW, Faulconbridge A, Cherubin L, Burdett T, Trigueros C, Patel MJ, Lucas C, Hardy B, Predan R, Dokler J, Brajnik M, Keminer O, Pless O, Gribbon P, Claussen C, Ringwald A, Kreisel B, Courtney A, Allsopp TE. De Sousa PA, et al. Among authors: ebneth a. Stem Cell Res. 2017 Apr;20:105-114. doi: 10.1016/j.scr.2017.03.002. Epub 2017 Mar 7. Stem Cell Res. 2017. PMID: 28334554 Free article.
Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.
Verheyen A, Diels A, Reumers J, Van Hoorde K, Van den Wyngaert I, van Outryve d'Ydewalle C, De Bondt A, Kuijlaars J, De Muynck L, De Hoogt R, Bretteville A, Jaensch S, Buist A, Cabrera-Socorro A, Wray S, Ebneth A, Roevens P, Royaux I, Peeters PJ. Verheyen A, et al. Among authors: ebneth a. Stem Cell Reports. 2018 Aug 14;11(2):363-379. doi: 10.1016/j.stemcr.2018.06.022. Epub 2018 Jul 26. Stem Cell Reports. 2018. PMID: 30057263 Free PMC article.
45 results