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Page 1
Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation.
Mijnheer G, Lutter L, Mokry M, van der Wal M, Scholman R, Fleskens V, Pandit A, Tao W, Wekking M, Vervoort S, Roberts C, Petrelli A, Peeters JGC, Knijff M, de Roock S, Vastert S, Taams LS, van Loosdregt J, van Wijk F. Mijnheer G, et al. Among authors: taams ls. Nat Commun. 2021 May 11;12(1):2710. doi: 10.1038/s41467-021-22975-7. Nat Commun. 2021. PMID: 33976194 Free PMC article.
Pulmonary SARS-CoV-2 infection leads to para-infectious immune activation in the brain.
Dunai C, Hetherington C, Boardman SA, Clark JJ, Sharma P, Subramaniam K, Tharmaratnam K, Needham EJ, Williams R, Huang Y, Wood GK, Collie C, Fower A, Fox H, Ellul MA, Held M, Egbe FN, Griffiths M, Solomon T, Breen G, Kipar A, Cavanagh J, Irani SR, Vincent A, Stewart JP, Taams LS, Menon DK, Michael BD. Dunai C, et al. Among authors: taams ls. Front Immunol. 2024 Oct 14;15:1440324. doi: 10.3389/fimmu.2024.1440324. eCollection 2024. Front Immunol. 2024. PMID: 39474424 Free PMC article.
TNF-α blockade induces IL-10 expression in human CD4+ T cells.
Evans HG, Roostalu U, Walter GJ, Gullick NJ, Frederiksen KS, Roberts CA, Sumner J, Baeten DL, Gerwien JG, Cope AP, Geissmann F, Kirkham BW, Taams LS. Evans HG, et al. Among authors: taams ls. Nat Commun. 2014;5:3199. doi: 10.1038/ncomms4199. Nat Commun. 2014. PMID: 24492460 Free PMC article.
The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells.
Perucha E, Melchiotti R, Bibby JA, Wu W, Frederiksen KS, Roberts CA, Hall Z, LeFriec G, Robertson KA, Lavender P, Gerwien JG, Taams LS, Griffin JL, de Rinaldis E, van Baarsen LGM, Kemper C, Ghazal P, Cope AP. Perucha E, et al. Among authors: taams ls. Nat Commun. 2019 Jan 30;10(1):498. doi: 10.1038/s41467-019-08332-9. Nat Commun. 2019. PMID: 30700717 Free PMC article.
Anti-TNF treatment negatively regulates human CD4+ T-cell activation and maturation in vitro, but does not confer an anergic or suppressive phenotype.
Povoleri GAM, Lalnunhlimi S, Steel KJA, Agrawal S, O'Byrne AM, Ridley M, Kordasti S, Frederiksen KS, Roberts CA, Taams LS. Povoleri GAM, et al. Among authors: taams ls. Eur J Immunol. 2020 Mar;50(3):445-458. doi: 10.1002/eji.201948190. Epub 2019 Dec 3. Eur J Immunol. 2020. PMID: 31722123 Free PMC article.
108 results