Govaerts C - Search Results

1

AlphaFold2 predicts the inward-facing conformation of the multidrug transporter LmrP.

Del Alamo D, Govaerts C, Mchaourab HS. Del Alamo D, et al. Among authors: govaerts c. Proteins. 2021 Sep;89(9):1226-1228. doi: 10.1002/prot.26138. Epub 2021 May 18. Proteins. 2021. PMID: 33973689 Free PMC article.

2

Protonation drives the conformational switch in the multidrug transporter LmrP.

Masureel M, Martens C, Stein RA, Mishra S, Ruysschaert JM, Mchaourab HS, Govaerts C. Masureel M, et al. Among authors: govaerts c. Nat Chem Biol. 2014 Feb;10(2):149-55. doi: 10.1038/nchembio.1408. Epub 2013 Dec 8. Nat Chem Biol. 2014. PMID: 24316739 Free PMC article.

3

Lipids modulate the conformational dynamics of a secondary multidrug transporter.

Martens C, Stein RA, Masureel M, Roth A, Mishra S, Dawaliby R, Konijnenberg A, Sobott F, Govaerts C, Mchaourab HS. Martens C, et al. Among authors: govaerts c. Nat Struct Mol Biol. 2016 Aug;23(8):744-51. doi: 10.1038/nsmb.3262. Epub 2016 Jul 11. Nat Struct Mol Biol. 2016. PMID: 27399258 Free PMC article.

4

An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity.

Debruycker V, Hutchin A, Masureel M, Ficici E, Martens C, Legrand P, Stein RA, Mchaourab HS, Faraldo-Gómez JD, Remaut H, Govaerts C. Debruycker V, et al. Among authors: govaerts c. Nat Struct Mol Biol. 2020 Sep;27(9):829-835. doi: 10.1038/s41594-020-0464-y. Epub 2020 Jul 27. Nat Struct Mol Biol. 2020. PMID: 32719456 Free PMC article.

5

Lipid composition regulates the orientation of transmembrane helices in HorA, an ABC multidrug transporter.

Gustot A, Smriti, Ruysschaert JM, McHaourab H, Govaerts C. Gustot A, et al. Among authors: govaerts c. J Biol Chem. 2010 May 7;285(19):14144-51. doi: 10.1074/jbc.M109.079673. Epub 2010 Mar 11. J Biol Chem. 2010. PMID: 20223819 Free PMC article.

6

Interactions between phosphatidylethanolamine headgroup and LmrP, a multidrug transporter: a conserved mechanism for proton gradient sensing?

Hakizimana P, Masureel M, Gbaguidi B, Ruysschaert JM, Govaerts C. Hakizimana P, et al. Among authors: govaerts c. J Biol Chem. 2008 Apr 4;283(14):9369-76. doi: 10.1074/jbc.M708427200. Epub 2008 Jan 30. J Biol Chem. 2008. PMID: 18234676 Free article.

7

LmrP from Lactoccoccus lactis: a tractable model to understand secondary multidrug transport in MFS.

Roth A, Govaerts C. Roth A, et al. Among authors: govaerts c. Res Microbiol. 2018 Sep-Oct;169(7-8):468-477. doi: 10.1016/j.resmic.2018.07.006. Epub 2018 Aug 23. Res Microbiol. 2018. PMID: 30145366 Free article. Review.

8

Identification of specific lipid-binding sites in integral membrane proteins.

Lensink MF, Govaerts C, Ruysschaert JM. Lensink MF, et al. Among authors: govaerts c. J Biol Chem. 2010 Apr 2;285(14):10519-26. doi: 10.1074/jbc.M109.068890. Epub 2010 Feb 5. J Biol Chem. 2010. PMID: 20139086 Free PMC article.

9

Metal binding properties and structure of a type III metallothionein from the metal hyperaccumulator plant Noccaea caerulescens.

Fernandez LR, Vandenbussche G, Roosens N, Govaerts C, Goormaghtigh E, Verbruggen N. Fernandez LR, et al. Among authors: govaerts c. Biochim Biophys Acta. 2012 Sep;1824(9):1016-23. doi: 10.1016/j.bbapap.2012.05.010. Epub 2012 Jun 2. Biochim Biophys Acta. 2012. PMID: 22668884

10

Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT₃ receptor via a common vestibule site.

Brams M, Govaerts C, Kambara K, Price KL, Spurny R, Gharpure A, Pardon E, Evans GL, Bertrand D, Lummis SC, Hibbs RE, Steyaert J, Ulens C. Brams M, et al. Among authors: govaerts c. Elife. 2020 Jan 28;9:e51511. doi: 10.7554/eLife.51511. Elife. 2020. PMID: 31990273 Free PMC article.

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