Zhang YK - Search Results

1

Exploring boron applications in modern agriculture: A structure-activity relationship study of a novel series of multi-substitution benzoxaboroles for identification of potential fungicides.

Liu C, Steere L, McGregor C, Frederick BH, Pastoor T, Zhou Y, Liu CT, Cai Y, Zhou H, Xu M, Wang J, Kim SH, Whitesell L, Cowen LE, Zhang YK. Liu C, et al. Among authors: zhang yk. Bioorg Med Chem Lett. 2021 Jul 1;43:128089. doi: 10.1016/j.bmcl.2021.128089. Epub 2021 May 5. Bioorg Med Chem Lett. 2021. PMID: 33964438

2

Inhibiting Protein Prenylation with Benzoxaboroles to Target Fungal Plant Pathogens.

Kim SH, Liu C, Zhou Y, Zhang YK, McGregor C, Steere L, Frederick BH, Liu CT, Whitesell L, Cowen LE. Kim SH, et al. Among authors: zhang yk. ACS Chem Biol. 2020 Jul 17;15(7):1930-1941. doi: 10.1021/acschembio.0c00290. Epub 2020 Jun 23. ACS Chem Biol. 2020. PMID: 32573189

3

Synthesis and antibacterial evaluation of a novel tricyclic oxaborole-fused fluoroquinolone.

Li X, Zhang YK, Plattner JJ, Mao W, Alley MR, Xia Y, Hernandez V, Zhou Y, Ding CZ, Li J, Shao Z, Zhang H, Xu M. Li X, et al. Among authors: zhang yk, zhang h. Bioorg Med Chem Lett. 2013 Feb 15;23(4):963-6. doi: 10.1016/j.bmcl.2012.12.045. Epub 2012 Dec 21. Bioorg Med Chem Lett. 2013. PMID: 23312945

4

Inhibiting C-4 Methyl Sterol Oxidase with Novel Diazaborines to Target Fungal Plant Pathogens.

Kim SH, Steere L, Zhang YK, McGregor C, Hahne C, Zhou Y, Liu C, Cai Y, Zhou H, Chen X, Puumala E, Duncan D, Wright GD, Liu CT, Whitesell L, Cowen LE. Kim SH, et al. Among authors: zhang yk. ACS Chem Biol. 2022 Jun 17;17(6):1343-1350. doi: 10.1021/acschembio.2c00257. Epub 2022 May 18. ACS Chem Biol. 2022. PMID: 35584803 Free PMC article.

5

Identification of a 4-fluorobenzyl l-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT).

Akama T, Zhang YK, Freund YR, Berry P, Lee J, Easom EE, Jacobs RT, Plattner JJ, Witty MJ, Peter R, Rowan TG, Gillingwater K, Brun R, Nare B, Mercer L, Xu M, Wang J, Liang H. Akama T, et al. Among authors: zhang yk. Bioorg Med Chem Lett. 2018 Jan 1;28(1):6-10. doi: 10.1016/j.bmcl.2017.11.028. Epub 2017 Nov 20. Bioorg Med Chem Lett. 2018. PMID: 29169674 Free PMC article.

6

Synthesis and structure-activity relationships of novel benzoxaboroles as a new class of antimalarial agents.

Zhang YK, Plattner JJ, Freund YR, Easom EE, Zhou Y, Gut J, Rosenthal PJ, Waterson D, Gamo FJ, Angulo-Barturen I, Ge M, Li Z, Li L, Jian Y, Cui H, Wang H, Yang J. Zhang YK, et al. Bioorg Med Chem Lett. 2011 Jan 15;21(2):644-51. doi: 10.1016/j.bmcl.2010.12.034. Epub 2010 Dec 10. Bioorg Med Chem Lett. 2011. PMID: 21195617

7

Optimization of isoxazoline amide benzoxaboroles for identification of a development candidate as an oral long acting animal ectoparasiticide.

Zhang YK, Plattner JJ, Easom EE, Akama T, Zhou Y, White WH, Defauw JM, Winkle JR, Balko TW, Cao J, Ge Z, Yang J. Zhang YK, et al. Bioorg Med Chem Lett. 2016 Jul 1;26(13):3182-3186. doi: 10.1016/j.bmcl.2016.04.093. Epub 2016 May 7. Bioorg Med Chem Lett. 2016. PMID: 27210432

8

Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles.

Zhang YK, Plattner JJ, Freund YR, Easom EE, Zhou Y, Ye L, Zhou H, Waterson D, Gamo FJ, Sanz LM, Ge M, Li Z, Li L, Wang H, Cui H. Zhang YK, et al. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1299-307. doi: 10.1016/j.bmcl.2011.12.096. Epub 2011 Dec 28. Bioorg Med Chem Lett. 2012. PMID: 22243961

9

Discovery of an orally bioavailable isoxazoline benzoxaborole (AN8030) as a long acting animal ectoparasiticide.

Zhang YK, Plattner JJ, Easom EE, Zhou Y, Akama T, Bu W, White WH, Defauw JM, Winkle JR, Balko TW, Guo S, Xue J, Cao J, Zou W. Zhang YK, et al. Bioorg Med Chem Lett. 2015 Dec 1;25(23):5589-93. doi: 10.1016/j.bmcl.2015.10.044. Epub 2015 Oct 23. Bioorg Med Chem Lett. 2015. PMID: 26508546

10

Discovery of novel P3-oxo inhibitor of hepatitis C virus NS3/4A serine protease.

Duan M, Kazmierski W, Crosby R, Gartland M, Ji J, Tallant M, Wang A, Hamatake R, Wright L, Wu M, Zhang YK, Ding CZ, Li X, Liu Y, Zhang S, Zhou Y, Plattner JJ, Baker SJ. Duan M, et al. Among authors: zhang s, zhang yk. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2993-6. doi: 10.1016/j.bmcl.2012.02.039. Epub 2012 Feb 22. Bioorg Med Chem Lett. 2012. PMID: 22425454

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