Kostyukova AS - Search Results

1

Autism-associated SHANK3 missense point mutations impact conformational fluctuations and protein turnover at synapses.

Bucher M, Niebling S, Han Y, Molodenskiy D, Hassani Nia F, Kreienkamp HJ, Svergun D, Kim E, Kostyukova AS, Kreutz MR, Mikhaylova M. Bucher M, et al. Among authors: kostyukova as. Elife. 2021 May 4;10:e66165. doi: 10.7554/eLife.66165. Elife. 2021. PMID: 33945465 Free PMC article.

2

The A31P missense mutation in cardiac myosin binding protein C alters protein structure but does not cause haploinsufficiency.

van Dijk SJ, Bezold Kooiker K, Mazzalupo S, Yang Y, Kostyukova AS, Mustacich DJ, Hoye ER, Stern JA, Kittleson MD, Harris SP. van Dijk SJ, et al. Among authors: kostyukova as. Arch Biochem Biophys. 2016 Jul 1;601:133-40. doi: 10.1016/j.abb.2016.01.006. Epub 2016 Jan 9. Arch Biochem Biophys. 2016. PMID: 26777460 Free PMC article.

3

Structural Effects of Disease-Related Mutations in Actin-Binding Period 3 of Tropomyosin.

Kuruba B, Kaczmarek M, Kęsik-Brodacka M, Fojutowska M, Śliwinska M, Kostyukova AS, Moraczewska J. Kuruba B, et al. Among authors: kostyukova as. Molecules. 2021 Nov 19;26(22):6980. doi: 10.3390/molecules26226980. Molecules. 2021. PMID: 34834072 Free PMC article.

4

Tropomodulin isoforms utilize specific binding functions to modulate dendrite development.

Gray KT, Suchowerska AK, Bland T, Colpan M, Wayman G, Fath T, Kostyukova AS. Gray KT, et al. Among authors: kostyukova as. Cytoskeleton (Hoboken). 2016 Jun;73(6):316-28. doi: 10.1002/cm.21304. Epub 2016 Jun 8. Cytoskeleton (Hoboken). 2016. PMID: 27126680 Free PMC article.

5

Structural destabilization of tropomyosin induced by the cardiomyopathy-linked mutation R21H.

Ly T, Krieger I, Tolkatchev D, Krone C, Moural T, Samatey FA, Kang C, Kostyukova AS. Ly T, et al. Among authors: kostyukova as. Protein Sci. 2018 Feb;27(2):498-508. doi: 10.1002/pro.3341. Epub 2017 Nov 21. Protein Sci. 2018. PMID: 29105867 Free PMC article.

6

Congenital myopathy-related mutations in tropomyosin disrupt regulatory function through altered actin affinity and tropomodulin binding.

Moraczewska J, Robaszkiewicz K, Śliwinska M, Czajkowska M, Ly T, Kostyukova A, Wen H, Zheng W. Moraczewska J, et al. FEBS J. 2019 May;286(10):1877-1893. doi: 10.1111/febs.14787. Epub 2019 Mar 5. FEBS J. 2019. PMID: 30768849 Free PMC article.

7

Structural insights into the tropomodulin assembly at the pointed ends of actin filaments.

Tolkatchev D, Kuruba B, Smith GE Jr, Swain KD, Smith KA, Moroz N, Williams TJ, Kostyukova AS. Tolkatchev D, et al. Among authors: kostyukova as. Protein Sci. 2021 Feb;30(2):423-437. doi: 10.1002/pro.4000. Epub 2020 Dec 2. Protein Sci. 2021. PMID: 33206408 Free PMC article.

8

Leiomodin creates a leaky cap at the pointed end of actin-thin filaments.

Tolkatchev D, Smith GE Jr, Schultz LE, Colpan M, Helms GL, Cort JR, Gregorio CC, Kostyukova AS. Tolkatchev D, et al. Among authors: kostyukova as. PLoS Biol. 2020 Sep 8;18(9):e3000848. doi: 10.1371/journal.pbio.3000848. eCollection 2020 Sep. PLoS Biol. 2020. PMID: 32898131 Free PMC article.

9

Role of tropomodulin's leucine rich repeat domain in the formation of neurite-like processes.

Guillaud L, Gray KT, Moroz N, Pantazis C, Pate E, Kostyukova AS. Guillaud L, et al. Among authors: kostyukova as. Biochemistry. 2014 Apr 29;53(16):2689-700. doi: 10.1021/bi401431k. Epub 2014 Apr 18. Biochemistry. 2014. PMID: 24746171 Free PMC article.

10

Effects of cardiomyopathy-linked mutations K15N and R21H in tropomyosin on thin-filament regulation and pointed-end dynamics.

Ly T, Pappas CT, Johnson D, Schlecht W, Colpan M, Galkin VE, Gregorio CC, Dong WJ, Kostyukova AS. Ly T, et al. Among authors: kostyukova as. Mol Biol Cell. 2019 Jan 15;30(2):268-281. doi: 10.1091/mbc.E18-06-0406. Epub 2018 Nov 21. Mol Biol Cell. 2019. PMID: 30462572 Free PMC article.

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