Zeymer C - Search Results

1

Analysis of electrostatic coupling throughout the laboratory evolution of a designed retroaldolase.

Coulther TA, Pott M, Zeymer C, Hilvert D, Ondrechen MJ. Coulther TA, et al. Among authors: zeymer c. Protein Sci. 2021 Aug;30(8):1617-1627. doi: 10.1002/pro.4099. Epub 2021 May 24. Protein Sci. 2021. PMID: 33938058 Free PMC article.

2

Efficient laboratory evolution of computationally designed enzymes with low starting activities using fluorescence-activated droplet sorting.

Obexer R, Pott M, Zeymer C, Griffiths AD, Hilvert D. Obexer R, et al. Among authors: zeymer c. Protein Eng Des Sel. 2016 Sep;29(9):355-66. doi: 10.1093/protein/gzw032. Epub 2016 Aug 19. Protein Eng Des Sel. 2016. PMID: 27542390

3

Optimization of Enzyme Mechanism along the Evolutionary Trajectory of a Computationally Designed (Retro-)Aldolase.

Zeymer C, Zschoche R, Hilvert D. Zeymer C, et al. J Am Chem Soc. 2017 Sep 13;139(36):12541-12549. doi: 10.1021/jacs.7b05796. Epub 2017 Aug 28. J Am Chem Soc. 2017. PMID: 28783336

4

Efficient laboratory evolution of computationally designed enzymes with low starting activities using fluorescence-activated droplet sorting.

Obexer R, Pott M, Zeymer C, Griffiths AD, Hilvert D. Obexer R, et al. Among authors: zeymer c. Protein Eng Des Sel. 2017 Jul 1;30(7):531. doi: 10.1093/protein/gzx032. Protein Eng Des Sel. 2017. PMID: 28873983 No abstract available.

5

Directed Evolution of Protein Catalysts.

Zeymer C, Hilvert D. Zeymer C, et al. Annu Rev Biochem. 2018 Jun 20;87:131-157. doi: 10.1146/annurev-biochem-062917-012034. Epub 2018 Mar 1. Annu Rev Biochem. 2018. PMID: 29494241 Review.

6

Emergence of a Negative Activation Heat Capacity during Evolution of a Designed Enzyme.

Bunzel HA, Kries H, Marchetti L, Zeymer C, Mittl PRE, Mulholland AJ, Hilvert D. Bunzel HA, et al. Among authors: zeymer c. J Am Chem Soc. 2019 Jul 31;141(30):11745-11748. doi: 10.1021/jacs.9b02731. Epub 2019 Jul 19. J Am Chem Soc. 2019. PMID: 31282667

7

Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion.

Caldwell SJ, Haydon IC, Piperidou N, Huang PS, Bick MJ, Sjöström HS, Hilvert D, Baker D, Zeymer C. Caldwell SJ, et al. Among authors: zeymer c. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30362-30369. doi: 10.1073/pnas.2008535117. Epub 2020 Nov 17. Proc Natl Acad Sci U S A. 2020. PMID: 33203677 Free PMC article.

8

Design and engineering of artificial metalloproteins: from de novo metal coordination to catalysis.

Klein AS, Zeymer C. Klein AS, et al. Among authors: zeymer c. Protein Eng Des Sel. 2021 Feb 15;34:gzab003. doi: 10.1093/protein/gzab003. Protein Eng Des Sel. 2021. PMID: 33635315 Review.

9

Americium preferred: lanmodulin, a natural lanthanide-binding protein favors an actinide over lanthanides.

Singer H, Drobot B, Zeymer C, Steudtner R, Daumann LJ. Singer H, et al. Among authors: zeymer c. Chem Sci. 2021 Oct 26;12(47):15581-15587. doi: 10.1039/d1sc04827a. eCollection 2021 Dec 8. Chem Sci. 2021. PMID: 35003587 Free PMC article.

10

Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins.

Hofmann R, Akimoto G, Wucherpfennig TG, Zeymer C, Bode JW. Hofmann R, et al. Among authors: zeymer c. Nat Chem. 2020 Nov;12(11):1008-1015. doi: 10.1038/s41557-020-0528-y. Epub 2020 Sep 14. Nat Chem. 2020. PMID: 32929246

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