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Combination of Bempegaldesleukin and Anti-CTLA-4 Prevents Metastatic Dissemination After Primary Resection or Radiotherapy in a Preclinical Model of Non-Small Cell Lung Cancer.
Bates AM, Brown RJ, Pieper AA, Zangl LM, Arthur I, Carlson PM, Le T, Sosa GA, Clark PA, Sriramaneni RN, Kim K, Patel RB, Morris ZS. Bates AM, et al. Among authors: clark pa. Front Oncol. 2021 Apr 15;11:645352. doi: 10.3389/fonc.2021.645352. eCollection 2021. Front Oncol. 2021. PMID: 33937052 Free PMC article.
Tumor-Specific Antibody, Cetuximab, Enhances the In Situ Vaccine Effect of Radiation in Immunologically Cold Head and Neck Squamous Cell Carcinoma.
Jin WJ, Erbe AK, Schwarz CN, Jaquish AA, Anderson BR, Sriramaneni RN, Jagodinsky JC, Bates AM, Clark PA, Le T, Lan KH, Chen Y, Kim K, Morris ZS. Jin WJ, et al. Among authors: clark pa. Front Immunol. 2020 Nov 12;11:591139. doi: 10.3389/fimmu.2020.591139. eCollection 2020. Front Immunol. 2020. PMID: 33281820 Free PMC article.
A multipurpose brachytherapy catheter to enable intratumoral injection.
Jagodinsky JC, Medeiros G, Raj HH, Razuan A, Locsin A, Dempsey TG, Tang B, Chakravarty I, Clark PA, Sriramaneni RN, Jin WJ, Lan KH, Das RK, Miller JR, Suarez-Gonzalez D, Morris ZS. Jagodinsky JC, et al. Among authors: clark pa. Brachytherapy. 2021 Jul-Aug;20(4):900-910. doi: 10.1016/j.brachy.2020.10.012. Epub 2021 Mar 27. Brachytherapy. 2021. PMID: 33785280 Free PMC article.
Low-Dose Radiation Potentiates the Propagation of Anti-Tumor Immunity against Melanoma Tumor in the Brain after In Situ Vaccination at a Tumor outside the Brain.
Clark PA, Sriramaneni RN, Bates AM, Jin WJ, Jagodinsky JC, Hernandez R, Le T, Jeffery JJ, Marsh IR, Grudzinski JJ, Aluicio-Sarduy E, Barnhart TE, Anderson BR, Chakravarty I, Arthur IS, Kim K, Engle JW, Bednarz BP, Weichert JP, Morris ZS. Clark PA, et al. Radiat Res. 2021 Jun 1;195(6):522-540. doi: 10.1667/RADE-20-00237.1. Radiat Res. 2021. PMID: 33826741 Free PMC article.
Multifunctional nanoparticle potentiates the in situ vaccination effect of radiation therapy and enhances response to immune checkpoint blockade.
Zhang Y, Sriramaneni RN, Clark PA, Jagodinsky JC, Ye M, Jin W, Wang Y, Bates A, Kerr CP, Le T, Allawi R, Wang X, Xie R, Havighurst TC, Chakravarty I, Rakhmilevich AL, O'Leary KA, Schuler LA, Sondel PM, Kim K, Gong S, Morris ZS. Zhang Y, et al. Among authors: clark pa. Nat Commun. 2022 Aug 23;13(1):4948. doi: 10.1038/s41467-022-32645-x. Nat Commun. 2022. PMID: 35999216 Free PMC article.
Local TLR4 stimulation augments in situ vaccination induced via local radiation and anti-CTLA-4 checkpoint blockade through induction of CD8 T-cell independent Th1 polarization.
Jagodinsky JC, Bates AM, Clark PA, Sriramaneni RN, Havighurst TC, Chakravarty I, Nystuen EJ, Kim K, Sondel PM, Jin WJ, Morris ZS. Jagodinsky JC, et al. Among authors: clark pa. J Immunother Cancer. 2022 Oct;10(10):e005103. doi: 10.1136/jitc-2022-005103. J Immunother Cancer. 2022. PMID: 36192087 Free PMC article.
NK cells propagate T cell immunity following in situ tumor vaccination.
Jin WJ, Jagodinsky JC, Vera JM, Clark PA, Zuleger CL, Erbe AK, Ong IM, Le T, Tetreault K, Berg T, Rakhmilevich AL, Kim K, Newton MA, Albertini MR, Sondel PM, Morris ZS. Jin WJ, et al. Among authors: clark pa. Cell Rep. 2023 Dec 26;42(12):113556. doi: 10.1016/j.celrep.2023.113556. Epub 2023 Dec 13. Cell Rep. 2023. PMID: 38096050 Free PMC article.
212 results