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Page 1
Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT.
Roberts I, Shakur-Still H, Aeron-Thomas A, Beaumont D, Belli A, Brenner A, Cargill M, Chaudhri R, Douglas N, Frimley L, Gilliam C, Geer A, Jamal Z, Jooma R, Mansukhani R, Miners A, Pott J, Prowse D, Shokunbi T, Williams J. Roberts I, et al. Among authors: frimley l. Health Technol Assess. 2021 Apr;25(26):1-76. doi: 10.3310/hta25260. Health Technol Assess. 2021. PMID: 33928903 Free PMC article. Clinical Trial.
Pharmacokinetics of intramuscular tranexamic acid in bleeding trauma patients: a clinical trial.
Grassin-Delyle S, Shakur-Still H, Picetti R, Frimley L, Jarman H, Davenport R, McGuinness W, Moss P, Pott J, Tai N, Lamy E, Urien S, Prowse D, Thayne A, Gilliam C, Pynn H, Roberts I. Grassin-Delyle S, et al. Among authors: frimley l. Br J Anaesth. 2021 Jan;126(1):201-209. doi: 10.1016/j.bja.2020.07.058. Epub 2020 Sep 30. Br J Anaesth. 2021. PMID: 33010927 Free article.
Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial.
Brenner A, Belli A, Chaudhri R, Coats T, Frimley L, Jamaluddin SF, Jooma R, Mansukhani R, Sandercock P, Shakur-Still H, Shokunbi T, Roberts I; CRASH-3 trial collaborators. Brenner A, et al. Among authors: frimley l. Crit Care. 2020 Nov 11;24(1):560. doi: 10.1186/s13054-020-03243-4. Crit Care. 2020. PMID: 33172504 Free PMC article. Clinical Trial.
Effect of early tranexamic acid treatment on fatigue in patients with mild traumatic brain injury: data from the CRASH-3 clinical trial.
Mansukhani R, Belli A, Brenner A, Chaudhri R, Frimley L, Faizah Jamaluddin S, Jooma R, Shakur-Still H, Shokunbi T, Roberts I. Mansukhani R, et al. Among authors: frimley l. Wellcome Open Res. 2024 Oct 28;6:346. doi: 10.12688/wellcomeopenres.17421.2. eCollection 2021. Wellcome Open Res. 2024. PMID: 39502454 Free PMC article.
Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients.
Gayet-Ageron A, Prieto-Merino D, Ker K, Shakur H, Ageron FX, Roberts I; Antifibrinolytic Trials Collaboration. Gayet-Ageron A, et al. Lancet. 2018 Jan 13;391(10116):125-132. doi: 10.1016/S0140-6736(17)32455-8. Epub 2017 Nov 7. Lancet. 2018. PMID: 29126600 Free PMC article.