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The Akt/GSK-3beta axis as a new signaling pathway of the histamine H(3) receptor.
Bongers G, Sallmen T, Passani MB, Mariottini C, Wendelin D, Lozada A, Marle Av, Navis M, Blandina P, Bakker RA, Panula P, Leurs R. Bongers G, et al. Among authors: leurs r. J Neurochem. 2007 Oct;103(1):248-58. doi: 10.1111/j.1471-4159.2007.04752.x. Epub 2007 Jul 10. J Neurochem. 2007. PMID: 17623045 Free article.
Activation of the histaminergic H3 receptor induces phosphorylation of the Akt/GSK-3 beta pathway in cultured cortical neurons and protects against neurotoxic insults.
Mariottini C, Scartabelli T, Bongers G, Arrigucci S, Nosi D, Leurs R, Chiarugi A, Blandina P, Pellegrini-Giampietro DE, Passani MB. Mariottini C, et al. Among authors: leurs r. J Neurochem. 2009 Sep;110(5):1469-78. doi: 10.1111/j.1471-4159.2009.06249.x. Epub 2009 Jun 22. J Neurochem. 2009. PMID: 19549072 Free article.
4-(3-Aminoazetidin-1-yl)pyrimidin-2-amines as High-Affinity Non-imidazole Histamine H3 Receptor Agonists with in Vivo Central Nervous System Activity.
Wágner G, Mocking TAM, Arimont M, Provensi G, Rani B, Silva-Marques B, Latacz G, Da Costa Pereira D, Karatzidou C, Vischer HF, Wijtmans M, Kieć-Kononowicz K, de Esch IJP, Leurs R. Wágner G, et al. Among authors: leurs r. J Med Chem. 2019 Dec 12;62(23):10848-10866. doi: 10.1021/acs.jmedchem.9b01462. Epub 2019 Nov 20. J Med Chem. 2019. PMID: 31675226 Free PMC article.
Covalent Inhibition of the Histamine H3 Receptor.
Wágner G, Mocking TAM, Kooistra AJ, Slynko I, Ábrányi-Balogh P, Keserű GM, Wijtmans M, Vischer HF, de Esch IJP, Leurs R. Wágner G, et al. Among authors: leurs r. Molecules. 2019 Dec 11;24(24):4541. doi: 10.3390/molecules24244541. Molecules. 2019. PMID: 31835873 Free PMC article.
414 results