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SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stress.
Zipin-Roitman A, Aqaqe N, Yassin M, Biechonski S, Amar M, van Delft MF, Gan OI, McDermott SP, Buzina A, Ketela T, Shlush L, Xie S, Voisin V, Moffat J, Minden MD, Dick JE, Milyavsky M. Zipin-Roitman A, et al. Among authors: milyavsky m. Oncotarget. 2017 Mar 7;8(10):16712-16727. doi: 10.18632/oncotarget.15147. Oncotarget. 2017. PMID: 28187429 Free PMC article.
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells.
Bao EL, Nandakumar SK, Liao X, Bick AG, Karjalainen J, Tabaka M, Gan OI, Havulinna AS, Kiiskinen TTJ, Lareau CA, de Lapuente Portilla AL, Li B, Emdin C, Codd V, Nelson CP, Walker CJ, Churchhouse C, de la Chapelle A, Klein DE, Nilsson B, Wilson PWF, Cho K, Pyarajan S, Gaziano JM, Samani NJ; FinnGen; 23andMe Research Team; Regev A, Palotie A, Neale BM, Dick JE, Natarajan P, O'Donnell CJ, Daly MJ, Milyavsky M, Kathiresan S, Sankaran VG. Bao EL, et al. Among authors: milyavsky m. Nature. 2020 Oct;586(7831):769-775. doi: 10.1038/s41586-020-2786-7. Epub 2020 Oct 14. Nature. 2020. PMID: 33057200 Free PMC article.
KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition.
Boila LD, Ghosh S, Bandyopadhyay SK, Jin L, Murison A, Zeng AGX, Shaikh W, Bhowmik S, Muddineni SSNA, Biswas M, Sinha S, Chatterjee SS, Mbong N, Gan OI, Bose A, Chakraborty S, Arruda A, Kennedy JA, Mitchell A, Lechman ER, Banerjee D, Milyavsky M, Minden MD, Dick JE, Sengupta A. Boila LD, et al. Among authors: milyavsky m. Leukemia. 2023 Apr;37(4):751-764. doi: 10.1038/s41375-023-01833-z. Epub 2023 Jan 31. Leukemia. 2023. PMID: 36720973
The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG.
Kugler E, Madiwale S, Yong D, Thoms JAI, Birger Y, Sykes DB, Schmoellerl J, Drakul A, Priebe V, Yassin M, Aqaqe N, Rein A, Fishman H, Geron I, Chen CW, Raught B, Liu Q, Ogana H, Liedke E, Bourquin JP, Zuber J, Milyavsky M, Pimanda J, Privé GG, Izraeli S. Kugler E, et al. Among authors: milyavsky m. Nat Commun. 2023 Sep 21;14(1):5871. doi: 10.1038/s41467-023-41067-2. Nat Commun. 2023. PMID: 37735473 Free PMC article.
Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signaling.
Louria-Hayon I, Frelin C, Ruston J, Gish G, Jin J, Kofler MM, Lambert JP, Adissu HA, Milyavsky M, Herrington R, Minden MD, Dick JE, Gingras AC, Iscove NN, Pawson T. Louria-Hayon I, et al. Among authors: milyavsky m. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20599-604. doi: 10.1073/pnas.1319665110. Epub 2013 Dec 2. Proc Natl Acad Sci U S A. 2013. PMID: 24297922 Free PMC article.
56 results