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Discovery of bakuchiol as an AIM2 inflammasome activator and cause of hepatotoxicity.
Liu T, Xu G, Li Y, Shi W, Ren L, Fang Z, Liang L, Wang Y, Gao Y, Zhan X, Li Q, Mou W, Lin L, Wei Z, Li Z, Dai W, Zhao J, Li H, Wang J, Zhao Y, Xiao X, Bai Z. Liu T, et al. Among authors: wang j, wang y. J Ethnopharmacol. 2022 Nov 15;298:115593. doi: 10.1016/j.jep.2022.115593. Epub 2022 Aug 13. J Ethnopharmacol. 2022. PMID: 35973629
Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7-NLRP3 interaction.
Li Q, Feng H, Wang H, Wang Y, Mou W, Xu G, Zhang P, Li R, Shi W, Wang Z, Fang Z, Ren L, Wang Y, Lin L, Hou X, Dai W, Li Z, Wei Z, Liu T, Wang J, Guo Y, Li P, Zhao X, Zhan X, Xiao X, Bai Z. Li Q, et al. Among authors: wang h, wang z, wang j, wang y. EMBO Rep. 2022 Feb 3;23(2):e53499. doi: 10.15252/embr.202153499. Epub 2021 Dec 9. EMBO Rep. 2022. PMID: 34882936 Free PMC article.
Neuregulin-1, a potential therapeutic target for cardiac repair.
Wang Y, Wei J, Zhang P, Zhang X, Wang Y, Chen W, Zhao Y, Cui X. Wang Y, et al. Front Pharmacol. 2022 Aug 31;13:945206. doi: 10.3389/fphar.2022.945206. eCollection 2022. Front Pharmacol. 2022. PMID: 36120374 Free PMC article. Review.
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