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Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
Chana CK, Maisonneuve P, Posternak G, Grinberg NGA, Poirson J, Ona SM, Ceccarelli DF, Mader P, St-Cyr DJ, Pau V, Kurinov I, Tang X, Deng D, Cui W, Su W, Kuai L, Soll R, Tyers M, Röst HL, Batey RA, Taipale M, Gingras AC, Sicheri F. Chana CK, et al. Among authors: kurinov i. J Med Chem. 2022 Oct 13;65(19):12725-12746. doi: 10.1021/acs.jmedchem.2c00509. Epub 2022 Sep 18. J Med Chem. 2022. PMID: 36117290 Free PMC article.
Effects of rigidity on the selectivity of protein kinase inhibitors.
Assadieskandar A, Yu C, Maisonneuve P, Liu X, Chen YC, Prakash GKS, Kurinov I, Sicheri F, Zhang C. Assadieskandar A, et al. Among authors: kurinov i. Eur J Med Chem. 2018 Feb 25;146:519-528. doi: 10.1016/j.ejmech.2018.01.053. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29407977 Free PMC article.
73 results