Miranda E - Search Results

1

G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic.

Ingwersen T, Linnenberg C, D'Acunto E, Temori S, Paolucci I, Wasilewski D, Mohammadi B, Kirchmair J, Glen RC, Miranda E, Glatzel M, Galliciotti G. Ingwersen T, et al. Among authors: miranda e. Sci Rep. 2021 Apr 22;11(1):8766. doi: 10.1038/s41598-021-88090-1. Sci Rep. 2021. PMID: 33888787 Free PMC article.

2

The intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB.

Miranda E, MacLeod I, Davies MJ, Pérez J, Römisch K, Crowther DC, Lomas DA. Miranda E, et al. Hum Mol Genet. 2008 Jun 1;17(11):1527-39. doi: 10.1093/hmg/ddn041. Epub 2008 Feb 11. Hum Mol Genet. 2008. PMID: 18267959 Free PMC article.

3

A novel interaction between aging and ER overload in a protein conformational dementia.

Schipanski A, Lange S, Segref A, Gutschmidt A, Lomas DA, Miranda E, Schweizer M, Hoppe T, Glatzel M. Schipanski A, et al. Among authors: miranda e. Genetics. 2013 Mar;193(3):865-76. doi: 10.1534/genetics.112.149088. Epub 2013 Jan 18. Genetics. 2013. PMID: 23335331 Free PMC article.

4

The stability and activity of human neuroserpin are modulated by a salt bridge that stabilises the reactive centre loop.

Noto R, Randazzo L, Raccosta S, Caccia S, Moriconi C, Miranda E, Martorana V, Manno M. Noto R, et al. Among authors: miranda e. Sci Rep. 2015 Sep 2;5:13666. doi: 10.1038/srep13666. Sci Rep. 2015. PMID: 26329378 Free PMC article.

5

Interactions between N-linked glycosylation and polymerisation of neuroserpin within the endoplasmic reticulum.

Moriconi C, Ordoñez A, Lupo G, Gooptu B, Irving JA, Noto R, Martorana V, Manno M, Timpano V, Guadagno NA, Dalton L, Marciniak SJ, Lomas DA, Miranda E. Moriconi C, et al. Among authors: miranda e. FEBS J. 2015 Dec;282(23):4565-79. doi: 10.1111/febs.13517. Epub 2015 Oct 3. FEBS J. 2015. PMID: 26367528 Free PMC article.

6

Embelin binds to human neuroserpin and impairs its polymerisation.

Saga G, Sessa F, Barbiroli A, Santambrogio C, Russo R, Sala M, Raccosta S, Martorana V, Caccia S, Noto R, Moriconi C, Miranda E, Grandori R, Manno M, Bolognesi M, Ricagno S. Saga G, et al. Among authors: miranda e. Sci Rep. 2016 Jan 6;6:18769. doi: 10.1038/srep18769. Sci Rep. 2016. PMID: 26732982 Free PMC article.

7

Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB.

Guadagno NA, Moriconi C, Licursi V, D'Acunto E, Nisi PS, Carucci N, De Jaco A, Cacci E, Negri R, Lupo G, Miranda E. Guadagno NA, et al. Among authors: miranda e. Neurobiol Dis. 2017 Jul;103:32-44. doi: 10.1016/j.nbd.2017.03.010. Epub 2017 Mar 28. Neurobiol Dis. 2017. PMID: 28363799 Free PMC article.

8

Cellular Models for the Serpinopathies.

Fra A, D'Acunto E, Laffranchi M, Miranda E. Fra A, et al. Among authors: miranda e. Methods Mol Biol. 2018;1826:109-121. doi: 10.1007/978-1-4939-8645-3_7. Methods Mol Biol. 2018. PMID: 30194596

9

Glycosylation Tunes Neuroserpin Physiological and Pathological Properties.

Visentin C, Broggini L, Sala BM, Russo R, Barbiroli A, Santambrogio C, Nonnis S, Dubnovitsky A, Bolognesi M, Miranda E, Achour A, Ricagno S. Visentin C, et al. Among authors: miranda e. Int J Mol Sci. 2020 May 3;21(9):3235. doi: 10.3390/ijms21093235. Int J Mol Sci. 2020. PMID: 32375228 Free PMC article.

10

Serpin neuropathology in the P497S UBQLN2 mouse model of ALS/FTD.

Higgins NR, Greenslade JE, Wu JJ, Miranda E, Galliciotti G, Monteiro MJ. Higgins NR, et al. Among authors: miranda e. Brain Pathol. 2021 Sep;31(5):e12948. doi: 10.1111/bpa.12948. Epub 2021 Mar 29. Brain Pathol. 2021. PMID: 33780087 Free PMC article.

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